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402474-85-5

402474-85-5 Structure

402474-85-5 Structure
IdentificationBack Directory
[Name]

Z-TYR-VAL-ALA-ASP-CHLOROMETHYLKETONE
[CAS]

402474-85-5
[Synonyms]

Z-YVAD-CMK
Z-TYR-VAL-ALA-ASP-CMK
Z-TYR-VAL-ALA-ASP-CMK: Z-YVAD-CMK
Z-TYR-VAL-ALA-ASP-CHLOROMETHYLKETONE
L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-tyrosyl-L-valyl-N-[(1S)-1-(carboxymethyl)-3-chloro-2-oxopropyl]- (9CI)
[Molecular Formula]

C30H37ClN4O9
[MDL Number]

MFCD00798795
[MOL File]

402474-85-5.mol
[Molecular Weight]

633.09
Chemical PropertiesBack Directory
[storage temp. ]

-15°C
[Sequence]

{Cbz}-Tyr-Val-Ala-Asp-{CMK}
Hazard InformationBack Directory
[Uses]

Z-YVAD-CMK is a caspase-1 and caspase-3 inhibitor[1].
[References]

[1] Knies UE, et al. Regulation of endothelial monocyte-activating polypeptide II release by apoptosis. Proc Natl Acad Sci U S A. 1998 Oct 13;95(21):12322-7. DOI:10.1073/pnas.95.21.12322
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