| Identification | Back Directory | [Name]
-5-chloro-3-(3,5-dibromo-4-hydroxybenzylidene)indolin-2-one | [CAS]
220904-99-4 | [Synonyms]
CID-25014542
Raf inhibitor 2
CID-25014542; CID25014542; CID 25014542
-5-chloro-3-(3,5-dibromo-4-hydroxybenzylidene)indolin-2-one
2H-Indol-2-one, 5-chloro-3-[(3,5-dibromo-4-hydroxyphenyl)methylene]-1,3-dihydro- | [Molecular Formula]
C15H8Br2ClNO2 | [MDL Number]
MFCD30186083 | [MOL File]
220904-99-4.mol | [Molecular Weight]
429.49 |
| Chemical Properties | Back Directory | [Boiling point ]
535.4±50.0 °C(Predicted) | [density ]
1.938±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 100 mg/mL (232.83 mM) | [form ]
Solid | [pka]
5.84±0.25(Predicted) | [color ]
White to yellow |
| Hazard Information | Back Directory | [Uses]
Raf inhibitor 2 is a potent raf kinase (IC50<1.0 μM) inhibitor, compound 32, extracted from patent EP1003721B1. Raf inhibitor 2 can be used for cancer research[1]. | [storage]
Store at -20°C | [References]
[1] German, et al. Benzylidene-1,3-dihydro-indol-2-one derivatives as receptor tyrosine kinase inhibitors, particularly of raf kinases. patent/EP1003721B1 |
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