| Identification | Back Directory | [Name]
9H-Xanthene-9-propanamine,N,N-dimethyl-2-(trifluoromethyl)- | [CAS]
22196-65-2 | [Synonyms]
9H-Xanthene-9-propanamine,N,N-dimethyl-2-(trifluoromethyl)- | [Molecular Formula]
C19H20F3NO | [MOL File]
22196-65-2.mol | [Molecular Weight]
335.363 |
| Hazard Information | Back Directory | [Uses]
SKF 10810 is a GABAA receptor antagonist with an EC50 of 4.3 μM. By blocking GABAergic inhibition of the brain's reward pathways, SKF 10810 may exert antidepressant effects. SKF 10810 can be used for research in neurological disorders[1]. | [References]
[1] Squires RF, et al. Antidepressants and metabolites that block GABAA receptors coupled to 35S-t-butylbicyclophosphorothionate binding sites in rat brain. Brain Res. 1988 Feb 16;441(1-2):15-22. DOI:10.1016/0006-8993(88)91378-9 |
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