| Identification | Back Directory | [Name]
Antidesmone | [CAS]
222629-77-8 | [Synonyms]
Antidesmone
(5S)-1,5,6,7-Tetrahydro-3-methoxy-2-methyl-5-octyl-4,8-quinolinedione
(5S)-3-methoxy-2-methyl-5-octyl-1,5,6,7-tetrahydroquinoline-4,8-dione
4,8-Quinolinedione, 1,5,6,7-tetrahydro-3-methoxy-2-methyl-5-octyl-, (5S)- | [Molecular Formula]
C19H29NO3 | [MDL Number]
MFCD20260974 | [MOL File]
222629-77-8.mol | [Molecular Weight]
319.438 |
| Chemical Properties | Back Directory | [Boiling point ]
468.3±45.0 °C(Predicted) | [density ]
1.07±0.1 g/cm3(Predicted) | [storage temp. ]
Store at 0-8 °C | [pka]
-4.58±0.70(Predicted) |
| Hazard Information | Back Directory | [Uses]
Antidesmone is a isoquinoline alkaloid that can be isolated from Antidesma membranaceum[1]. Antidesmone can prevent acute lung injury in vivo via inhibiting MAPK and NF-κb activities[2]. | [References]
[1] Lu X, et al. Antidesmone, a unique tetrahydroquinoline alkaloid, prevents acute lung injury via regulating MAPK and NF-κB activities. Int Immunopharmacol. 2017 Apr;45:34-42. DOI:10.1016/j.intimp.2017.01.026
[2] Buske, et al. Antidesmone, a novel type isoquinoline alkaloid from Antidesma membranaceum (Euphorbiaceae). Tetrahedron, 55(4), 1079–1086. |
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