| Identification | Back Directory | [Name]
TL 13-22 | [CAS]
2229036-65-9 | [Synonyms]
TL 13-22
Acetamide, N-[2-[2-[2-[4-[4-[[5-chloro-4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-2-pyrimidinyl]amino]-3-methoxyphenyl]-1-piperazinyl]ethoxy]ethoxy]ethyl]-2-[[2,3-dihydro-1,3-dioxo-2-(2-oxo-3-piperidinyl)-1H-isoindol-4-yl]amino]- | [Molecular Formula]
C45H55ClN10O9S | [MOL File]
2229036-65-9.mol | [Molecular Weight]
947.5 |
| Hazard Information | Back Directory | [Uses]
TL13-22 is a negative control for TL13-12 (HY-122582) and a potent ALK inhibitor with an IC50 of 0.54 nM. TL13-22 does not degrade ALK in cells[1]. | [storage]
Store at -20°C | [References]
[1] Chelsea E Powell, et al. Chemically Induced Degradation of Anaplastic Lymphoma Kinase (ALK). J Med Chem. 2018 May 10;61(9):4249-4255. DOI:10.1021/acs.jmedchem.7b01655 |
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| Company Name: |
BOC Sciences
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| Tel: |
16314854226 |
| Website: |
www.bocsci.com |
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