ChemicalBook--->CAS DataBase List--->222988-10-5

222988-10-5

222988-10-5 Structure

222988-10-5 Structure
IdentificationBack Directory
[Name]

H-THR-PRO-ASP-ILE-ASN-PRO-ALA-TRP-TYR-THR-GLY-ARG-GLY-ILE-ARG-PRO-VAL-GLY-ARG-PHE-NH2
[CAS]

222988-10-5
[Synonyms]

PRRP20
PRRP20 (RAT)
PubChem ID: 24868197
TPDINPAWYTGRGIRPVGRF-NH2
PREPROLACTIN (34-53) (RAT)
Rat prolactin-releasing peptide-20
PROLACTIN-RELEASING PEPTIDE (12-31)
Rat prolactin-releasing peptide 12-31
PrRP20 (rat), Preprolactin (34-53) (rat)
PROLACTIN-RELEASING PEPTIDE (12-31) (RAT)
THR-PRO-ASP-ILE-ASN-PRO-ALA-TRP-TYR-THR-GLY-ARG-GLY-ILE-ARG-PRO-VAL-GLY-ARG-PHE-NH2
H-THR-PRO-ASP-ILE-ASN-PRO-ALA-TRP-TYR-THR-GLY-ARG-GLY-ILE-ARG-PRO-VAL-GLY-ARG-PHE-NH2
[Molecular Formula]

C104H158N32O26
[MDL Number]

MFCD02094632
[MOL File]

222988-10-5.mol
[Molecular Weight]

2272.57
Chemical PropertiesBack Directory
[density ]

1.50±0.1 g/cm3(Predicted)
[storage temp. ]

−20°C
[form ]

Solid
[color ]

White to off-white
[Sequence]

Thr-Pro-Asp-Ile-Asn-Pro-Ala-Trp-Tyr-Thr-Gly-Arg-Gly-Ile-Arg-Pro-Val-Gly-Arg-Phe-NH2
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

Prolactin-Releasing Peptide (12-31), rat is a fragment of the prolactin releasing peptide (PrRP). Prolactin-Releasing Peptide (12-31), rat shows high affinity for GPR10 receptors. Prolactin-Releasing Peptide (12-31), stimulates calcium mobilization in CHOK1 cells transfected with the PrRP receptor[1][2].
[References]

[1] Roland BL, et al. Anatomical distribution of prolactin-releasing peptide and its receptor suggests additional functions in the central nervous system and periphery. Endocrinology. 1999 Dec;140(12):5736-45. DOI:10.1210/endo.140.12.7211
[2] Langmead CJ, et al. Characterization of the binding of [(125)I]-human prolactin releasing peptide (PrRP) to GPR10, a novel G protein coupled receptor. Br J Pharmacol. 2000 Oct;131(4):683-8. DOI:10.1038/sj.bjp.0703617
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