| Identification | Back Directory | [Name]
Pyrazolo[4,3-b]pyrido[4,3-e][1,4]diazepine, 5-(2-chlorophenyl)-1,2-dihydro-3-methyl-8-(4-morpholinyl)- | [CAS]
2230490-29-4 | [Synonyms]
Tinengotinib
Tinengotinib (TT-00420)
Tinengotinib (TT-00420, TT00420)
Pyrazolo[4,3-b]pyrido[4,3-e][1,4]diazepine, 5-(2-chlorophenyl)-1,2-dihydro-3-methyl-8-(4-morpholinyl)- | [Molecular Formula]
C20H19ClN6O | [MOL File]
2230490-29-4.mol | [Molecular Weight]
394.86 |
| Chemical Properties | Back Directory | [Boiling point ]
665.9±55.0 °C(Predicted) | [density ]
1.51±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
16.32±0.40(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
Tinengotinib is the modulator of one or more protein kinases such as Aurora kinase and VEGFR kinase. Tinengotinib has the potential for the research of these kinase abnormalities diseases mediated, especially cancer-related diseases (extracted from patent WO2018108079A1)[1]. | [References]
[1] Wu, Yongqian, et al. Multi-kinase inhibitor compound, and crystal form and use thereof. Patent WO2018108079A1. |
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