ChemicalBook--->CAS DataBase List--->223500-15-0

223500-15-0

223500-15-0 Structure

223500-15-0 Structure
IdentificationBack Directory
[Name]

1H-Pyrazole-4-carboxylic acid, 1-(4-aminophenyl)-5-(trifluoromethyl)-, ethyl ester
[CAS]

223500-15-0
[Synonyms]

PDE4-IN-20
ethyl 1-(4-aminophenyl)-5-(trifluoromethyl)pyrazole-4-carboxylate
1H-Pyrazole-4-carboxylic acid, 1-(4-aminophenyl)-5-(trifluoromethyl)-, ethyl ester
ethyl 1(4aminophenyl)5(trifluoromethyl)1Hpyrazole4carboxylate,ethyl 1 (4 aminophenyl) 5 (trifluoromethyl) 1H pyrazole 4 carboxylate
[Molecular Formula]

C13H12F3N3O2
[MDL Number]

MFCD00729039
[MOL File]

223500-15-0.mol
[Molecular Weight]

299.25
Chemical PropertiesBack Directory
[Melting point ]

107-109 °C
[Boiling point ]

413.2±45.0 °C(Predicted)
[density ]

1.39±0.1 g/cm3(Predicted)
[pka]

2.68±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

PDE4-IN-16 (compound 27) is a PDE4 inhibitor with an IC50 value of 3.61 μM. PDE4-IN-16 can be used for the research of inflammatory diseases and central nervous system (CNS) disorders involving elevated levels of cytokines[1].
[References]

[1] Timothy J. Martins, et al. Pyrazole cyclic amp-specific pde inhibitors. .U.S. WO2001046172, 2001-06-28.
Spectrum DetailBack Directory
[Spectrum Detail]

1H-Pyrazole-4-carboxylic acid, 1-(4-aminophenyl)-5-(trifluoromethyl)-, ethyl ester(223500-15-0)1HNMR
223500-15-0 suppliers list
Company Name: Tianjin Kailiqi Biotechnology Co., Ltd.  
Telephone: 15076683720
Website: http://www.cw-bio.com
Company Name: Yantai ShengKailun Chemical Technology Co., Ltd.  
Telephone: 13356901049
Website: www.sklnchem.cn
Company Name: TargetMol Chemicals Inc.  
Telephone: 4008200310 15002144251
Website: https://www.targetmol.cn/
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
Telephone: 021-65675885 18964387627
Website: http://www.efebio.com
Company Name: Shanghai Amole Biotechnology Co., Ltd.  
Telephone: 13370042665 18916960931
Website: www.amole.com.cn/
Company Name: Shanghai Yaoheping Biopharmaceutical Technology Co., Ltd  
Telephone: 57540919 13120888836
Website:
Company Name: Guangzhou Ruidi Biotechnology Co., Ltd.  
Telephone: 020-82099279 18988941402
Website: www.ubiochem.com/
Tags:223500-15-0 Related Product Information
29925-17-5 608141-41-9 68550-75-4 93882-12-3 171596-29-5 73963-72-1