ChemicalBook--->CAS DataBase List--->2244161-72-4

2244161-72-4

Request For Quotation
2244161-72-4 Structure

2244161-72-4 Structure
IdentificationBack Directory
[Name]

Dolutegravir Impurity 8
[CAS]

2244161-72-4
[Synonyms]

2,6-Di fluoro Dolutegravir
2,6 Difluoro dolutegravir sodium salt
Dolutegravir 2,6-Difluoro Analog (Dolutegravir 4-Desfluoro 6-Fluoro Impurity)
4-Desfluoro-6-fluoro DolutegravirQ: What is 4-Desfluoro-6-fluoro Dolutegravir Q: What is the CAS Number of 4-Desfluoro-6-fluoro Dolutegravir
(4R,12aS)-N-(2,6-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,6-difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-
[Molecular Formula]

C20H19F2N3O5
[MOL File]

2244161-72-4.mol
[Molecular Weight]

419.38
Chemical PropertiesBack Directory
[Boiling point ]

664.9±55.0 °C(Predicted)
[density ]

1.53±0.1 g/cm3(Predicted)
[pka]

4.50±1.00(Predicted)
Hazard InformationBack Directory
[Uses]

4-Desfluoro-6-fluoro Dolutegravir is impurity C of Dolutegravir (D528800), which is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.
2244161-72-4 suppliers list
Company Name: S.Z. PhyStandard Bio-Tech. Co., Ltd.  
Telephone: 0755-4000505016 13380397412
Website: www.sincopharmachem.net
Company Name: Shanghai Kewel Chemical Co., Ltd.  
Telephone: 021-64609169 18901607656
Website: http://www.kewelchem.com/
Company Name: Hubei Yangxin Medical Technology Co., Ltd.  
Telephone: 15374522761
Website: www.standardpharm.org.cn/
Company Name: TOSUN PHARM  
Telephone: 020-66392521-118 18922260391
Website: www.toref.cn/
Company Name: CR Corporation Limited  
Telephone:
Website: http://www.crcorporation.cn/
Company Name: sgtlifesciences pvt ltd  
Telephone: +91-8790379245
Website: https://www.chemicalbook.com/ShowSupplierProductsList1846349/0.htm
Company Name: Guangzhou Jiuzhi Pharmaceutical Technology Co., Ltd.  
Telephone: 020-89854820
Website: http://www.jzpharma.cn
Company Name: Chongqing Meixing Pharmaceutical Technology Co., Ltd.  
Telephone: 15023715366
Website: https://www.chemicalbook.com/ShowSupplierProductsList612309/0_EN.htm
Company Name: Wuxi Helen Biotechnology Co., Ltd.,  
Telephone: 0510-85629785 18013409632
Website: http://www.reading-chemicals.com
Company Name: Shandong WorldSun Biological Technology Co., Ltd.  
Telephone: 0531-88723173 18596073690
Website: https://www.worldsun-chem.com/
Company Name: QUALITY CONTROL SOLUTIONS LTD.  
Telephone: +86-0755-66853366 +86-13670046396
Website: https://www.qcsrm.com
Company Name: Molcoo Chemicals Inc.  
Telephone: 18627923403
Website: www.molcoo.com/
Company Name: Shenzhen Roark Pharma-Tec Co., Ltd.  
Telephone: 13128912434
Website: www.chemicalbook.com/showsupplierproductslist1522230/0_en.htm
Company Name: Scinova Biotech(Guangzhou) Co., Ltd.  
Telephone: 13268215580
Website: www.scinova-e.com/
Company Name: HX Pharmaceutical technology co., LTD  
Telephone: 15671363360
Website: www.szhx-pharm.com
Company Name: Aurisco Pharmaceutical (Tianjin) Inc.  
Telephone: 022-59885855
Website: www.aurisco.com
Company Name: Guangzhou Zhenlin Pharmaceutical Technology Co., Ltd  
Telephone: 020-18102736 13622807357
Website:
Company Name: ShenZhen H&D Pharmaceutical Technology Co., LTD  
Telephone: 18126517264
Website: www.hdimpurity.com/
Tags:2244161-72-4 Related Product Information
1802141-49-6 2244161-71-3 1309560-49-3 1916490-96-4 1357289-29-2