ChemicalBook--->CAS DataBase List--->2253878-44-1

2253878-44-1

2253878-44-1 Structure

2253878-44-1 Structure
IdentificationBack Directory
[Name]

BCL6-IN-3
[CAS]

2253878-44-1
[Synonyms]

BCL6-IN-3
CCT369260
[Molecular Formula]

C24H31ClF2N6O2
[MDL Number]

MFCD32878244
[MOL File]

2253878-44-1.mol
[Molecular Weight]

508.99
Chemical PropertiesBack Directory
[Boiling point ]

640.1±65.0 °C(Predicted)
[density ]

1.38±0.1 g/cm3(Predicted)
[solubility ]

DMSO: Sparingly soluble: 1-10 mg/ml
[pka]

15.14±0.29(Predicted)
[InChIKey]

VFNPUAOAEFMXQI-GASCZTMLNA-N
[SMILES]

C1(=O)N(C)C2=CC=C(NC3C(Cl)=CN=C(N4C[C@H](C)C(F)(F)[C@H](C)C4)N=3)C=C2N1CCC(O)(C)C |&1:17,22,r|
Hazard InformationBack Directory
[Description]

CCT369260 is a potent BCL6 degrader.
[References]

[1] BENJAMIN R. BELLENIE. Achieving In Vivo Target Depletion through the Discovery and Optimization of Benzimidazolone BCL6 Degraders[J]. Journal of Medicinal Chemistry, 2020, 63 8: 4047-4068. DOI: 10.1021/acs.jmedchem.9b02076
Spectrum DetailBack Directory
[Spectrum Detail]

BCL6-IN-3(2253878-44-1)1HNMR
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