| Identification | More | [Name]
VITAMIN H | [CAS]
22879-79-4 | [Synonyms]
5-((3AR,6S,6AS)-2-OXO-HEXAHYDRO-THIENO[3,4-D]IMIDAZOL-6-YL)-PENTANOIC ACID
BIOEPIDERM
BIOS H
(+)-BIOTIN
BIOTIN
BIOTIN, IMMOBILIZED ON DEXTRAN
BIOTIN, IMMOBILIZED ON DEXTRAN-LYSINE
BIOTINUM
BIOTIN(V-H)
CIS-HEXAHYDRO-2-OXO-1H-THIENE[3,4]IMIDAZOLE-4-VALERIC ACID
COENZYME R
D(+)-BIOTIN
D-BIOTIN
D-CIS-HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOLE-4-PENTANOIC ACID
FACTOR S
HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOLE-4-PENTANOIC ACID
PHOTOPROBE(R) BIOTIN
RONACARE(TM) BIOTIN PLUS
VITAMIN B7
VITAMIN H | [EINECS(EC#)]
200-399-3 | [Molecular Formula]
C10H16N2O3S | [MDL Number]
MFCD00005541 | [Molecular Weight]
244.31 | [MOL File]
22879-79-4.mol |
| Chemical Properties | Back Directory | [Melting point ]
231-233 °C(lit.) | [storage temp. ]
2-8°C
| [solubility ]
H2O: 0.2 mg/mL Solubility increases with addition of 1 N NaOH.
| [form ]
powder
| [color ]
White to Off-White | [Cosmetic Ingredient Review (CIR)]
VITAMIN H (22879-79-4) | [InChI]
InChI=1/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6?,7-,9?/s3 | [InChIKey]
YBJHBAHKTGYVGT-OGHHUDDSNA-N | [SMILES]
O=C1NC2[C@H](CCCCC(=O)O)SCC2N1 |&1:4,r| | [Uses]
biotin (biotine; vitamin B7/vitamin H) is anti-seborrhoeic. Some cosmetic manufacturers claim biotin has healing properties and as such, is a good ingredient for treating acne skin. Biotin is also part of the B complex group of vitamins (specifically vitamin B7). A deficiency of this vitamin has been associated with greasy scalp and baldness. Its deficiency in humans is considered extremely rare, and the value of external applications through the use of cosmetic products is questionable. | [CAS DataBase Reference]
22879-79-4(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Physical properties]
Appearance: biotin is a white crystalline substance. Stability: it is fairly stable to air,
heat, and light in dry form. In solution, however, it tends to degrade under strongly
acidic or basic conditions. In the eight possible stereoisomers of biotin, only the
(+)-isomer (called d-biotin) has biological activity. Biotin is covalently bound to its
enzymes by an amide bond to the ε-amino group of a lysine residue and C-2 of the
thiophane nucleus. The biotin molecule is activated by polarization of the O and
N-1’atoms of the ureido nucleus. This leads to increased nucleophilicity at N-1′,
which promotes the formation of a covalent bond between the electrophilic car bonyl phosphate formed from bicarbonate and ATP, and allows biotin to serve as a
transport agent for CO2. | [Definition]
ChEBI:Biotin is an organic heterobicyclic compound that consists of 2-oxohexahydro-1H-thieno[3,4-d]imidazole having a valeric acid substituent attached to the tetrahydrothiophene ring. The parent of the class of biotins. It has a role as a prosthetic group, a coenzyme, a nutraceutical, a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a mouse metabolite, a cofactor and a fundamental metabolite. It is a member of biotins and a vitamin B7. It is a conjugate acid of a biotinate. | [Brand name]
Bioepiderm (Sterling Winthrop). |
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