Identification | Back Directory | [Name]
1H-Pyrazolo[4,3-c]pyridine-7-carboxamide, 5-[(3,4-dichlorophenyl)methyl]-4,5-dihydro-4-oxo-1-(4-piperidinyl)-N-4-pyridinyl- | [CAS]
2290660-61-4 | [Synonyms]
BDP-13176 1H-Pyrazolo[4,3-c]pyridine-7-carboxamide, 5-[(3,4-dichlorophenyl)methyl]-4,5-dihydro-4-oxo-1-(4-piperidinyl)-N-4-pyridinyl- | [Molecular Formula]
C24H22Cl2N6O2 | [MOL File]
2290660-61-4.mol | [Molecular Weight]
497.38 |
Chemical Properties | Back Directory | [Boiling point ]
779.9±60.0 °C(Predicted) | [density ]
1.50±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 125 mg/mL (251.32 mM) | [form ]
Solid | [pka]
10.68±0.20(Predicted) | [color ]
White to off-white |
Hazard Information | Back Directory | [Uses]
BDP-13176 is a potent fascin 1 inhibitor, with a Kd of 90 nM and an IC50 of 240 nM. BDP-13176 has potential as an anti-metastatic agent[1]. | [storage]
Store at -20°C | [References]
[1] Francis S, et al. Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents. Bioorg Med Chem Lett. 2019;29(8):1023-1029. DOI:10.1016/j.bmcl.2019.01.035 |
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Company Name: |
InvivoChem
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Tel: |
13549236410 |
Website: |
https://www.invivochem.cn/ |
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