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2290660-61-4

2290660-61-4 Structure

2290660-61-4 Structure
IdentificationBack Directory
[Name]

1H-Pyrazolo[4,3-c]pyridine-7-carboxamide, 5-[(3,4-dichlorophenyl)methyl]-4,5-dihydro-4-oxo-1-(4-piperidinyl)-N-4-pyridinyl-
[CAS]

2290660-61-4
[Synonyms]

BDP-13176
1H-Pyrazolo[4,3-c]pyridine-7-carboxamide, 5-[(3,4-dichlorophenyl)methyl]-4,5-dihydro-4-oxo-1-(4-piperidinyl)-N-4-pyridinyl-
[Molecular Formula]

C24H22Cl2N6O2
[MOL File]

2290660-61-4.mol
[Molecular Weight]

497.38
Chemical PropertiesBack Directory
[Boiling point ]

779.9±60.0 °C(Predicted)
[density ]

1.50±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: 125 mg/mL (251.32 mM)
[form ]

Solid
[pka]

10.68±0.20(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

BDP-13176 is a potent fascin 1 inhibitor, with a Kd of 90 nM and an IC50 of 240 nM. BDP-13176 has potential as an anti-metastatic agent[1].
[storage]

Store at -20°C
[References]

[1] Francis S, et al. Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents. Bioorg Med Chem Lett. 2019;29(8):1023-1029. DOI:10.1016/j.bmcl.2019.01.035
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