| Identification | More | [Name]
4,16-ANDROSTADIEN-3-BETA-OL | [CAS]
23062-06-8 | [Synonyms]
4,16-ANDROSTADIEN-3-β-OL
4,16-ANDROSTADIEN-3-BETA-OL
4,16-Anfrostadien-3-beta-OI
Androsta-4,16-dien-3-ol,(3b)-
Androsta-4,16-dien-3-ol, (3β)- | [Molecular Formula]
C19H28O | [MDL Number]
MFCD00271236 | [Molecular Weight]
272.43 | [MOL File]
23062-06-8.mol |
| Chemical Properties | Back Directory | [form ]
Solid | [color ]
White to off-white | [InChI]
InChI=1/C19H28O/c1-18-9-3-4-16(18)15-6-5-13-12-14(20)7-11-19(13,2)17(15)8-10-18/h3,9,12,14-17,20H,4-8,10-11H2,1-2H3/t14-,15-,16-,17-,18-,19-/s3 | [InChIKey]
NYVFCEPOUVGTNP-KRHBYBJCNA-N | [SMILES]
[C@@H]1(O)C=C2[C@](C)(CC1)[C@]1([H])[C@]([H])([C@@]3([H])[C@@](CC1)(C)C=CC3)CC2 |&1:0,4,8,10,12,14,r| | [CAS DataBase Reference]
23062-06-8(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Uses]
Fasedienol (PH94B) is a neurochemical stimulator of the vomeronasal organ (VON). Fasedienol significantly increases Ca++. Fasedienol modulates the olfactory amygdala circuitry of fear and anxiety to alleviate symptoms of PMS and anxiety[1][2][3]. | [References]
[1] Clive L. Jennings-White, et al. Steroids as neurochemical stimulators of the vno to alleviate symptoms of anxiety. Patent WO1998014194A1.
[2] Monti L, et al. Effect of fasedienol (PH94B) pherine nasal spray and steroidal hormones on electrogram responses and autonomic nervous system activity in healthy adult volunteers[J]. Human Psychopharmacology: Clinical and Experimental, 2024, 39(2): e2892. DOI:10.1002/hup.2892
[3] Monti L, et al. Neural circuits of anxiolytic and antidepressant pherine molecules. CNS Spectr. 2022 Feb;27(1):66-72. DOI:10.1017/S109285292000190X |
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