2309172-24-3

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2309172-24-3 Structure

Identification	Back Directory
[Name] ABO (hydrochloride)
[CAS] 2309172-24-3
[Synonyms] ABO (hydrochloride) 6-amino-3,4-dihydro-2H-1,4-benzoxazine-3-methanol,dihydrochloride
[Molecular Formula] C9H14Cl2N2O2
[MOL File] 2309172-24-3.mol
[Molecular Weight] 253.126

Hazard Information	Back Directory
[Uses] ABO hydrochloride is a potent modulator of ANXA7 as ABO binds to Thr286 of ANXA7 and inhibits its phosphorylation. ABO promotes autophagy via elevation of ANXA7 and triggering ANXA7 subcellular redistribution[1].
[References] [1] Li H, et al. Identification of a small molecule targeting annexin A7. Biochim Biophys Acta. 2013 Sep;1833(9):2092-9. DOI:10.1016/j.bbamcr.2013.04.015

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