ChemicalBook--->CAS DataBase List--->23142-01-0

23142-01-0

23142-01-0 Structure

23142-01-0 Structure
IdentificationBack Directory
[Name]

CARBETAPENTANE CITRATE
[CAS]

23142-01-0
[Synonyms]

toclase
Atomin S
Gai-Less
Takabetan
Astomatop
loucarbate
pentoxyverine citr
PENTOXIVERINE CITRATE
PENTOXYVERINE CITRATE
Pnetoxyverine citrate
carbetapentonecitrate
CARETAPENTANE CITRATE
CARBETAPENTANE CITRATE
CARBETAPENTANE CITRATE SALT
CARBETAPENTANE CITRATE USP/EP/BP
Carbetapentane citrate/Pentoxyverine citrate
1-PHENYLCYCLOPENTANECARBOXYLIC ACID [2-DIETHYLAMINOETHOXY]ETHYL ESTER
2-(DiethylaMinoethoxy)ethyl 1-Phenyl-1-cyclopentanecarboxylate Citrate
2-(2-(diethylamino)ethoxy)-ethano1-phenylcyclopentanecarboxylate(ester)
2-(2(diethylamino)ethoxy)ethyl1-phenyl-cyclopentanecarboxylatecitrate(1:1)
2-(2-(diethylamino)ethoxy)ethyl1-phenylcyclopentyl-1-carboxylatedihydrogen
1-Phenylcyclopentane-1-carboxylic Acid DiethylaMinoethoxyethyl Ester Citrate
1-PHENYLCYCLOPENTANECARBOXYLIC ACID 2-(2-DIETHYLAMINOETHOXY)ETHYL ESTER CITRATE
1-PHENYLCYCLOPENTANECARBOXYLIC ACID 2-(2-DIETHYLAMINO-ETHOXY)ETHYL ESTER CITRATE SALT
Carbetapentane citrate salt,1-Phenylcyclopentanecarboxylic acid 2-(2-diethylaminoethoxy)ethyl ester citrate salt
diethyl[2-[2-[(1-phenylcyclopentyl)formyloxy]ethoxy]ethyl]ammonium dihydrogen 2-hydroxypropane-1,2,3-tricarboxylate
Cyclopentanecarboxylic acid, 1-phenyl-, 2-[2-(diethylamino)ethoxy]ethyl ester, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
[EINECS(EC#)]

245-449-5
[Molecular Formula]

C26H39NO10
[MDL Number]

MFCD00055697
[MOL File]

23142-01-0.mol
[Molecular Weight]

525.59
Chemical PropertiesBack Directory
[Melting point ]

84-86?C
[storage temp. ]

Sealed in dry,2-8°C
[solubility ]

H2O: soluble
[form ]

Solid
[color ]

White to Off-White
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

20/21/22-36/37/38
[Safety Statements ]

26-36
[WGK Germany ]

3
[RTECS ]

GY3500000
Hazard InformationBack Directory
[Chemical Properties]

White to Off-White Solid
[Originator]

Asthma ,Nichiiko
[Uses]

An over-the-counter cough suppressant.
[Uses]

antibacterial, antiproliferative
[Definition]

ChEBI: Carbetapentane citrate is a carbonyl compound.
[Manufacturing Process]

1-Phenylcyclopentane carbonitrile was obtained by treatment of phenylacetonitrile with sodium amide and 1,4-dibrombutane.
1-Phenyl-1-cyclopentane carboxylic acid was produced in the result of reaction of 1-phenylcyclopentane carbonitrile with sulfuric acid.
1-Phenyl-1-cyclopentanecarbonyl chloride was obtained by treatment of 1phenyl-1-cyclopentane carboxylic acid with thionyl chloride.
A mixture of 0.5 mol of 1-phenyl-1-cyclopentanecarbonyl chloride and of 0.5 mol of 2-(2-diethylaminoethoxy)ethanol (herein-after referred to as the amino alcohol) in 300 ml of toluene is heated under reflux for 20 h. The mixture is thereafter made alkaline by means of an aqueous solution of caustic soda and decanted; the toluenic layer is washed with water and concentrated in vacuo. The residue is distilled under high vacuum. After two fractional distillations, the 2-(2-diethylaminoethoxy)ethyl 1-phenylcyclopentane-carboxylate is obtained, in 85% yield. Boiling point 164°C/0.1 mm. Hg.
[Brand name]

Toclase (Pfizer).
[Therapeutic Function]

Antitussive
[Biological Activity]

A selective ligand for the σ 1 -site.
[storage]

Store at -20°C
Spectrum DetailBack Directory
[Spectrum Detail]

CARBETAPENTANE CITRATE(23142-01-0)1HNMR
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