| Identification | Back Directory | [Name]
Protein kinase inhibitors 1 hydrochloride | [CAS]
2321337-71-5 | [Synonyms]
Protein kinase inhibitor 1 hydrochloride | [Molecular Formula]
C18H18ClN5O3S | [MDL Number]
MFCD31807310 | [MOL File]
2321337-71-5.mol | [Molecular Weight]
419.88 |
| Hazard Information | Back Directory | [Uses]
Protein kinase inhibitor 1 hydrochloride is a potent HIPK2 inhibitor, with IC50s of 136 and 74 nM for HIPK1 and HIPK2, and a Kd of 9.5 nM for HIPK2. | [IC 50]
DYRK1; DYRK2 | [References]
[1] Miduturu CV, et al. High-throughput kinase profiling: a more efficient approach toward the discovery of new kinaseinhibitors. Chem Biol. 2011 Jul 29;18(7):868-79. DOI:10.1016/j.chembiol.2011.05.010 |
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