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2321337-71-5

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2321337-71-5 Structure

2321337-71-5 Structure
IdentificationBack Directory
[Name]

Protein kinase inhibitors 1 hydrochloride
[CAS]

2321337-71-5
[Synonyms]

Protein kinase inhibitor 1 hydrochloride
[Molecular Formula]

C18H18ClN5O3S
[MDL Number]

MFCD31807310
[MOL File]

2321337-71-5.mol
[Molecular Weight]

419.88
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

Protein kinase inhibitor 1 hydrochloride is a potent HIPK2 inhibitor, with IC50s of 136 and 74 nM for HIPK1 and HIPK2, and a Kd of 9.5 nM for HIPK2.
[IC 50]

DYRK1; DYRK2
[References]

[1] Miduturu CV, et al. High-throughput kinase profiling: a more efficient approach toward the discovery of new kinaseinhibitors. Chem Biol. 2011 Jul 29;18(7):868-79. DOI:10.1016/j.chembiol.2011.05.010
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