| Identification | More | [Name]
2-BENZIMIDAZOLEPROPIONIC ACID | [CAS]
23249-97-0 | [Synonyms]
2-BENZIMIDAZOLEPROPIONIC ACID
3-(1H-1,3-BENZIMIDAZOL-2-YL)PROPANOIC ACID
3-(1H-BENZIMIDAZOL-2-YL)PROPANOIC ACID
3-(1H-BENZOIMIDAZOL-2-YL)-PROPIONIC ACID
AKOS AUF2065
(BENZIMIDAZOLYL)PROPIONIC ACID
IFLAB-BB F0852-0156
(2-benzimidazolyl)propionicacid
1h-benzimidazole-2-propanoicacid
2-(2-benzimidazolyl)-propionicaci
2-(2-carboxyethyl)benzimidazole
beta-(2-benzimidazole)propionicacid
beta-(2-benzimidazolyl)propionicacid
procodazol
procodazole
2-BENZIMIDAZOLEPROPIONIC ACID 97%
1H-Benzimidazole-2-propanoicacid(9CI)
propazole
1H-Benzimidazole-2-propionic acid
3-(1H-Benzoimidazole-2-yl)propanoic acid | [Molecular Formula]
C10H10N2O2 | [MDL Number]
MFCD00041215 | [Molecular Weight]
190.2 | [MOL File]
23249-97-0.mol |
| Chemical Properties | Back Directory | [Melting point ]
229-231 °C (dec.)(lit.) | [Boiling point ]
497.9±28.0 °C(Predicted) | [density ]
1.367±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : ≥ 30 mg/mL (157.73 mM) | [form ]
Solid | [pka]
3.98±0.10(Predicted) | [color ]
White to off-white | [Merck ]
13,7851 | [InChI]
InChI=1S/C10H10N2O2/c13-10(14)6-5-9-11-7-3-1-2-4-8(7)12-9/h1-4H,5-6H2,(H,11,12)(H,13,14) | [InChIKey]
XYWJNTOURDMTPI-UHFFFAOYSA-N | [SMILES]
C1(CCC(O)=O)NC2=CC=CC=C2N=1 | [CAS DataBase Reference]
23249-97-0(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [RTECS ]
UE7480000
| [HazardClass ]
IRRITANT | [HS Code ]
29332990 |
| Hazard Information | Back Directory | [Uses]
2-Benzimidazolepropionic acid is suitable reagent for use in the method of generation of monoclonal antibodies against very small drug hapten, 5-benzimidazolecarboxylic acid by in vivo immunisation method and an in vitro immunisation procedure. It may be used in the synthesis of cytidine derivatives. | [Uses]
immune stimulant | [Definition]
ChEBI: Procodazole is a member of benzimidazoles. | [General Description]
2-Benzimidazolepropionic acid is a 2-(4-thiazolyl)benzimidazole analog. 2-Benzimidazolepropionic acid is a 2-substituted benzimidazole ligand and its dissociation constant has been evaluated. 2-Benzimidazolepropionic acid is reported to possess active antimarial activity. | [in vivo]
Procodazole (50 mg per dog, p.o., once daily for 28 days) can significantly reduce the parasite burden in Beagles infected with Toxocara canis and enhance their resistance to Toxocara canisinfection[1]. | Animal Model: | Three-month-old Beagle puppies infected with 3000 embryonated Toxocara canis eggs[2] | | Dosage: | 50 mg per dog | | Administration: | Oral gavage (p.o.), once daily for 28 days | | Result: | Reduced the number of worms significantly in the treated group compared to the untreated group, with a 63.8% reduction in worm burden. |
| [IC 50]
CA Ⅸ: 8.35 μM (IC50) | [storage]
Store at -20°C |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Sigma-Aldrich
|
| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
|