| Identification | Back Directory | [Name]
Decursinol | [CAS]
23458-02-8 | [Synonyms]
ecursinol
23458-02-8
Decursinol
(3S)-3-Hydroxy-2,2-dimethyl-3,4-dihydropyrano[3,2-g]chromen-8-one
(S)-7,8-Dihydro-7-hydroxy-8,8-dimethyl-2H,6H-benzo[1,2-b:5,4-b']dipyran-2-one
(7S)-7α-Hydroxy-8,8-dimethyl-7,8-dihydro-2H,6H-benzo[1,2-b:5,4-b']dipyran-2-one
2H,6H-Benzo[1,2-b:5,4-b']dipyran-2-one,7,8-dihydro-7-hydroxy-8,8-dimethyl-, (7S)- | [Molecular Formula]
C14H14O4 | [MDL Number]
MFCD06636641 | [MOL File]
23458-02-8.mol | [Molecular Weight]
246.261 |
| Chemical Properties | Back Directory | [Melting point ]
178 °C | [Boiling point ]
433.6±45.0 °C(Predicted) | [density ]
1.293±0.06 g/cm3(Predicted) | [storage temp. ]
4°C, protect from light | [solubility ]
DMF: 30 mg/ml; DMSO: 15 mg/ml; Ethanol: slightly soluble | [form ]
A solid | [pka]
13.87±0.40(Predicted) | [color ]
White to off-white | [Cosmetics Ingredients Functions]
SKIN CONDITIONING
ANTIOXIDANT | [CAS DataBase Reference]
23458-02-8 |
| Hazard Information | Back Directory | [Uses]
Decursinol, isolated from the roots of Angelica gigas, possesses antinociceptive effect with orally bioavailability. Decursinol possesses anti-tumor and anti-metastasis activity[1]. | [Definition]
ChEBI: An organic heterotricyclic compound that is 7,8-dihydro-2H,6H-pyrano[3,2-g]chromen-2-one substituted by a beta-hydroxy group at position 7 and two methyl groups at position 8. It is isolat
d from the roots of Angelica gigas and has been found to possess significant inhibitory activity against acetylcholinesterase enzyme (EC 3.1.1.7). | [storage]
4°C, protect from light | [References]
[1] Choi SS, et al. Antinociceptive mechanisms of orally administered decursinol in the mouse. Life Sci. 2003 Jun 13;73(4):471-85. DOI:10.1016/s0024-3205(03)00311-4
[2] Son SH, et al. Decursin and decursinol from Angelica gigas inhibit the lung metastasis of murine colon carcinoma. Phytother Res. 2011 Jul;25(7):959-64. DOI:10.1002/ptr.3372 |
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