| Identification | Back Directory | [Name]
pimpinellin | [CAS]
131-12-4 | [Synonyms]
Pimpinecilin
5,6-dimethoxyfuro[2,3-h]chromen-2-one
5,6-DiMethoxy-2H-furo[2,3-h]chroMen-2-one
5,6-Dimethoxy-2H-furo[2,3-h]-1-benzopyran-2-one
2H-Furo[2,3-h]-1-benzopyran-2-one, 5,6-dimethoxy- | [Molecular Formula]
C13H10O5 | [MDL Number]
MFCD00597237 | [MOL File]
131-12-4.mol | [Molecular Weight]
246.22 |
| Chemical Properties | Back Directory | [Melting point ]
119° | [Boiling point ]
441.0±45.0 °C(Predicted) | [density ]
1.352±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
powder | [color ]
Yellow | [InChI]
InChI=1S/C13H10O5/c1-15-11-7-3-4-9(14)18-10(7)8-5-6-17-12(8)13(11)16-2/h3-6H,1-2H3 | [InChIKey]
BQPRWZCEKZLBHL-UHFFFAOYSA-N | [SMILES]
C1(=O)OC2C3C=COC=3C(OC)=C(OC)C=2C=C1 | [LogP]
1.477 (est) |
| Hazard Information | Back Directory | [Chemical Properties]
Light yellow needle-shaped crystals, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Radix Angelicae Pubescentis. | [Uses]
GABA receptor antagonist, phototoxin | [Definition]
ChEBI: Pimpinellin is a furanocoumarin. | [Biological Activity]
Pimpinellin is a coumarin isolated from roots of Angelica dahurica and Zosima absinthifolia th at exhibits anti-tumoranti-allergicantioxidant and anticholinesterase activities. It appears to reduce the release of histaminesecretion of TBF-αinterleukin (IL)-1β and IL-4. Pimpinellin exhibits potent cytotoxic activities against MGC-803PC3and A375 cancer cell lines. | [storage]
-20°C, protect from light |
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