| Identification | Back Directory | [Name]
Peimine | [CAS]
23496-41-5 | [Synonyms]
PEIMINE
Verticin
VERTICINE
PAYNANTHEINE(SH)
Peimine USP/EP/BP
Peimine(Verticine)
Dihydroisoimperialine
ISODIHYDROIMPERIALINE
(5α)-Cevane-3β,6α,20-triol
Cevane-3,6,20-triol, (3β,5α,6α)-
Imperialine Impurity 2 (Peimine)
(3beta,5alpha,6alpha)-Cevane-3,6,20-triol
Peimine, 98%, from Fritillaria cirrhosa D. Don
(3S,4aS,5S,6aS,6bS,8aS,9S,9aS,12S,15aS,15bR,16aS,16bR)-9,12,16b-Trimethyltetracosahydrobenzo[4,5]indeno[1,2-h]pyrido[1,2-b]isoquinoline-3,5,9-triol | [Molecular Formula]
C27H45NO3 | [MDL Number]
MFCD02259442 | [MOL File]
23496-41-5.mol | [Molecular Weight]
431.65 |
| Chemical Properties | Back Directory | [Melting point ]
223-224° | [alpha ]
D16 -19.4° (ethanol); D17 -20° (CHCl3) | [Boiling point ]
568.4±50.0 °C(Predicted) | [density ]
1.18±0.1 g/cm3(Predicted) | [storage temp. ]
under inert gas (nitrogen or Argon) at 2–8 °C | [solubility ]
Acetonitrile (Slightly, Heated, Sonicated), Chloroform (Slightly), Ethanol (Slightly) | [form ]
Solid | [pka]
9.5(at 25℃) | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Description]
Fritillaria verticillata var. Thunbergii also yields this steroidal alkaloid which was originally given the formulae ClsH3302N or C19H3S02N. The base has [α]10D -10.66° (EtOH), yields a crystalline perchlorate, a platinichloride, and contains three non-phenolic hydroxyl groups. The nitrogen atom is tertiary in character. Chi and his colleagues regard the alkaloid as identical with Peimine (q.v.).
| [Uses]
Peimine is a steroidal alkaloid compound extracted from the Fritillaria species of medicinal plants. | [Definition]
ChEBI: Verticine is an alkaloid. | [References]
Fukuda., Sci. Rep. Tohoku Imp. Univ., 18,323 (1929)
Chi, Kao, Chang.,i. Amer. Chern. Soc., 58, 1306 (1936)
Chi, Kao, Chang., ibid, 62, 1778 (1944) |
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