| Identification | Back Directory | [Name]
VOMIFOLIOL | [CAS]
23526-45-6 | [Synonyms]
VOMIFOLIOL
Blumenol A
(6S,9R)-vomifoliol
(S)-4-Hydroxy-4-[(R,E)-3-hydroxy-1-butenyl]-3,5,5-trimethyl-2-cyclohexen-1-one
(1S)-1-Hydroxy-1-[(1E,3R)-3-hydroxy-1-butenyl]-2,6,6-trimethyl-2-cyclohexene-4-one
2-Cyclohexen-1-one,4-hydroxy-4-[(1E,3R)-3-hydroxy-1-buten-1-yl]-3,5,5-triMethyl-, (4S)- | [Molecular Formula]
C13H20O3 | [MDL Number]
MFCD20260591 | [MOL File]
23526-45-6.mol | [Molecular Weight]
224.3 |
| Chemical Properties | Back Directory | [Melting point ]
115 °C | [Boiling point ]
362.3±42.0 °C(Predicted) | [density ]
1.130±0.06 g/cm3(Predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
12.72±0.60(Predicted) | [color ]
White to off-white | [LogP]
1.479 (est) |
| Hazard Information | Back Directory | [Uses]
Vomifoliol, a compound related to abscisie acid (ABA), has a modified 2,4-pentadiene side chain and has activity equal to that displayed by ABA. Vomifoliol exhibits antiacetylcholinesterase activity and displays moderate antileishmanial activity[1][2]. | [Definition]
ChEBI: (6S,9R)-vomifoliol is a (6S)-vomifoliol with a R configuration for the hydroxy group at position 9. It has a role as a phytotoxin and a metabolite. It is an enantiomer of a (6R,9S)-vomifoliol. | [target]
NF-kB | HIF | VEGFR | [References]
[1] Stuart KL, et al. The effect of vomifoliol on stomatal aperture. Planta. 1975;122(3):307-310. DOI:10.1007/BF00385281
[2] Mogana R, et al. The antiacetylcholinesterase and antileishmanial activities of Canarium patentinervium Miq. Biomed Res Int. 2014;2014:903529. DOI:10.1155/2014/903529 |
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