| Identification | Back Directory | [Name]
BENFLUOREX HYDROCHLORIDE | [CAS]
23602-78-0 | [Synonyms]
s992
s780
S-780
se780
jp992
SE-780
D07192
Minolip
Mediaxal
BENFLUREX
BRN 4152887
benfluramate
Mediaxal (tn)
Benfluorex - API
Benfluorex (inn/ban)
Benzoyloxyfenfluramine
N-(2-Benzoyloxyethyl)norfenfluramine
Benfluorex (base and/or unspecified salts)
1-(m-Trifluoromethylphenyl)-2-(benzoyloxy)ethylaminopropane
2-(alpha-methyl-m-trifluoromethylphenethylamino)-ethanobenzoate
2-(alpha-methyl-m-trifluoromethylphenethylamino)ethanolbenzoate
2-(alpha-Methyl-m-trifluoromethylphenethylamino)ethanol benzoate
Ethanol, 2-(alpha-methyl-m-trifluoromethylphenethylamino)-, benzoate
2-((1-Methyl-2-[3-(trifluoromethyl)phenyl]ethyl)amino)ethyl benzoate
Benzoic acid 2-[(α-methyl-3-trifluoromethylphenethyl)amino]ethyl ester
n-(2-hydroxyethyl)-alpha-methyl-m-trifluoromethyl-phenethylaminbenzoate
n-(2-hydroxyethyl)-alpha-methyl-m-trifluoromethylphenethylaminebenzoate
N-(2-Hydroxyethyl)-alpha-methyl-m-trifluoromethylphenethylamine benzoate
benzoic acid 2-[1-[3-(trifluoromethyl)phenyl]propan-2-ylamino]ethyl ester
Ethanol, 2-[[1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl]amino]-, benzoate
n-(1-methyl-2-(3-[trifluoromethyl]-phenyl)ethyl]aminoethanol benzoate ester
Ethanol, 2-[[1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl]amino]-, 1-benzoate
2-[[alpha-Methyl-m-(trifluoromethyl)phenethyl]amino]ethanol benzoate (ester)
Phenethylamine, N-(2-hydroxyethyl)-alpha-methyl-m-trifluoromethyl-, benzoate
Benzoic acid 2-[[1-methyl-2-(3-trifluoromethylphenyl)ethyl]amino]ethyl ester | [EINECS(EC#)]
245-777-9 | [Molecular Formula]
C19H20F3NO2 | [MDL Number]
MFCD00242709 | [MOL File]
23602-78-0.mol | [Molecular Weight]
351.36 |
| Hazard Information | Back Directory | [Originator]
Mediator,Servier,France,1976 | [Uses]
antihyperlipoproteinemic | [Definition]
ChEBI:Benzoic acid 2-[1-[3-(trifluoromethyl)phenyl]propan-2-ylamino]ethyl ester is a benzoate ester. | [Manufacturing Process]
To a solution of 24.7 parts of 1-(m-trifluoromethylphenyl)-2-(β-
hydroxyethyl)amino propane in 140 parts of anhydrous benzene, there were
added successively 15 parts of 4.7N hydrochloric ether and a solution of 14
parts of benzoyl chloride in 24 parts of anhydrous benzene. The addition
required 10 minutes, the reaction mixture was then refluxed for 8 hours.
The solid product was collected by filtration and after recrystallization from
230 parts of ethyl acetate, there were obtained 15 parts of 1-(mtrifluoromethylphenyl)-
2-(β-benzoyloxyethyl)amino propane hydrochloride
melting at 161°C.
10 parts hydrochloride are put in suspension in 100 parts of water, 80 parts
ether are added, then 10 parts of a concentrated solution of ammonium
hydroxide. The mixture is stirred a few minutes until the salt is dissolved,
then the ethered solution is poured off and dried. After the ether is
eliminated, 9 parts of 1-(m-trifluoromethylphenyl)-2-(β-
benzoyloxyethyl)amino propane are obtained; the base is a colorless oil. | [Therapeutic Function]
Antihyperlipidemic, Cardiovascular |
|
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LGM Pharma
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HBCChem, Inc.
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InvivoChem
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Carbosynth
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Leancare Ltd.
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SIGMA-RBI
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www.sigma-aldrich.com |
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