| Identification | Back Directory | [Name]
1H-Isoindole-1,3(2H)-dione, 4-[(6-aminohexyl)amino]-2-(1-methyl-2,6-dioxo-3-piperidinyl)- | [CAS]
2375536-48-2 | [Synonyms]
1H-Isoindole-1,3(2H)-dione, 4-[(6-aminohexyl)amino]-2-(1-methyl-2,6-dioxo-3-piperidinyl)- | [Molecular Formula]
C20H26N4O4 | [MOL File]
2375536-48-2.mol | [Molecular Weight]
386.44 |
| Hazard Information | Back Directory | [Uses]
N-Me-Thalidomide-NH-C6-NH2 is an E3 ligase ligand-linker conjugate. N-Me-Thalidomide-NH-C6-NH2 can be used to synthesize Anti-inflammatory agent 70 (HY-157570)[1]. | [References]
[1] Jin Liu, et al. Novel CRBN-Recruiting Proteolysis-Targeting Chimeras as Degraders of Stimulator of Interferon Genes with In Vivo Anti-Inflammatory Efficacy. Journal of Medicinal Chemistry. 2022 65 (9), 6593-6611 DOI:10.1021/acs.jmedchem.1c01948 |
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