| Identification | Back Directory | [Name]
Ethenesulfonamide, N-[4-(2-naphthalenylmethyl)phenyl]- | [CAS]
2380228-45-3 | [Synonyms]
DC-TEADin02
Ethenesulfonamide, N-[4-(2-naphthalenylmethyl)phenyl]- | [Molecular Formula]
C19H17NO2S | [MOL File]
2380228-45-3.mol | [Molecular Weight]
323.41 |
| Chemical Properties | Back Directory | [Boiling point ]
501.7±53.0 °C(Predicted) | [density ]
1.268±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
8.23±0.50(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
DC-TEADin02 is a potent TEAD autopalmitoylation inhibitor. DC-TEADin02 has TEAD autopalmitoylation inhibitory with the IC50 value of 197 nM. DC-TEADin02 can be used for the research of development, regeneration and tissue homeostasis[1]. | [References]
[1] Wenchao Lu, et al. Discovery and biological evaluation of vinylsulfonamide derivatives as highly potent, covalent TEAD autopalmitoylation inhibitors. Eur J Med Chem. 2019 Dec 15;184:111767. DOI:10.1016/j.ejmech.2019.111767 |
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