Chemical Properties | Back Directory | [solubility ]
可溶于甲醇,DMF等有机溶剂,极易溶于水 | [Appearance]
Dark blue solid | [ex/em]
678/706 nm (PBS buffer) | [ε(extinction coefficient)]
211000 L⋅mol−1⋅cm−1 | [Φ(quantum yield)]
0.21 |
Hazard Information | Back Directory | [Uses]
Sulfo-Cyanine5.5 azide tripotassium, a near-infrared (NIR) fluorescent dye, is an azide-functionalized Sulfo-Cyanine5.5 (Ex=678 nm, Em=694 nm). Sulfo-Cyanine5.5 azide tripotassium can react with alkynes for Click Chemistry labeling[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. | [References]
[1] Katrin Spinnler, et al. An Alkyne-functionalized Arginine for Solid-Phase Synthesis Enabling "Bioorthogonal" Peptide Conjugation. ACS Med Chem Lett. 2019 Sep 30;11(3):334-339. DOI:10.1021/acsmedchemlett.9b00388 |
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