| Identification | More | [Name]
7-CHLORO-4-HYDRAZINOQUINOLINE | [CAS]
23834-14-2 | [Synonyms]
1-(7-CHLORO-4-QUINOLYL)HYDRAZINE
7-CHLORO-4-HYDRAZINOQUINOLINE
BUTTPARK 45\09-14
LABOTEST-BB LT00452674
TIMTEC-BB SBB000320
7-chloro-4-hydrazino-quinolin
7-chloro-4-quinolylhydrazine
(7-Chloroquinoline-4-yl)hydrazine | [Molecular Formula]
C9H8ClN3 | [MDL Number]
MFCD00006776 | [Molecular Weight]
193.63 | [MOL File]
23834-14-2.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [RTECS ]
VB2900000
|
| Hazard Information | Back Directory | [Uses]
7-Chloro-4-hydrazinoquinoline was used in the preparation of new Schiff base hydrazone ligand via reaction with o-hydroxybenzaldehyde. It was also used in the preparation of N′-(E)-heteroaromatic-isonicotinohydrazide derivatives and the heteroaromatic 7-chloro-4-quinolinylhydrazone derivatives. | [Synthesis]
7-chloro-4-hydrazinoquinoline is prepared by hydrazine monohydrate and 4,7-dichloroquinoline in absolute ethanol.Hydrazine monohydrate (2022 mg, 40.0 mmol) and 4,7-dichloroquinoline (800 mg,
4.00 mmol) were dissolved in absolute ethanol (50 ml). The reaction mixture was
left under reflux until the reaction has gone to completion and then allowed to cool
in the ice bath for crystallization to occur.93 (676 mg, 87%): mp: 220 – 225 ℃ (Lit.:
223 – 225 ℃);
vmax/cm-1 3320 w (N-H), 3050 w (aro. C-H), 1607 m (C=N), 1448
(m, aro. C=C); δH (300 MHz; DMSO-d6) 11.09 (br. s., NH), 8.56-8.40 (2H, m,
C(5)H and C(2)H), 7.97 (1H, d, J 1.9, C(8)H), 7.70 (1H, dd, J 9.0, 1.9, C(6)H), 7.10
(1H, d, J 7.2, C(3)H), 5.31 (br. s., NH); δC (75 MHz; DMSO-d6) 155.7 (Ar-C),
142.4 (C(2)H), 138.7 (Ar-C), 137.6 (Ar-C), 126.4 (C(6)H), 125.3 (C(5)H), 119.1
(C(8)H), 113.6 (Ar-C), 98.1 (C(3)H); m/z (-ES) 194 (100%, [M+H]- with 35Cl),
196 (27%, [M+H]- with 37Cl); found by +ES 194.0475, C9H9ClN3 ([M+H]+ with
35Cl), requires 194.0480, error 2.6 ppm. |
|
| Company Name: |
Energy Chemical
|
| Tel: |
021-021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
|