| Identification | Back Directory | [Name]
2-Hydrazino-4,6-dimethylpyrimidine | [CAS]
23906-13-0 | [Synonyms]
2-Hydrazino-4
4,6-Dimethyl-2-hydrazinopyrimidine
2-Hydrazino-4,6-dimethylpyrimidine
4,6-dimethyl-2-hydrazinylpyrimidine
2-hydrazineyl-4,6-dimethylpyrimidine
Pyrimidine, 2-hydrazinyl-4,6-dimethyl-
2-Hydrazino-4,6-dimethylpyrimidine Solution
2(1H)-Pyrimidinone, 4,6-dimethyl-, hydrazone
2-hydrazino-4,6-dimethylpyrimidine(SALTDATA: FREE)
2-Hydrazino-4,6-dimethylpyrimidine ISO 9001：2015 REACH
2(1H)-Pyrimidinone, 4,6-dimethyl-, hydrazone (7CI,9CI) | [Molecular Formula]
C6H10N4 | [MDL Number]
MFCD00094479 | [MOL File]
23906-13-0.mol | [Molecular Weight]
138.17 |
| Chemical Properties | Back Directory | [Melting point ]
165 °C | [Boiling point ]
256.0±23.0 °C(Predicted) | [density ]
1.26±0.1 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,Store in freezer, under -20°C | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
6.44±0.70(Predicted) | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Synthesis]
General procedure for the synthesis of 2-hydrazino-4,6-dimethylpyrimidines using 2-chloro-4,6-dimethylpyrimidines as starting material: hydrazine monohydrate (1.02 mL, 21.0 mmol) was slowly added to a solution of ethanol (5 mL) containing 2-chloro-4,6-dimethylpyrimidines (2 g, 14.0 mmol). The reaction mixture was stirred continuously for 2 hours at room temperature. Upon completion of the reaction, the precipitate precipitated was collected by vacuum filtration and washed with cold methanol. The resulting solid was dried under a stream of air to give 2-hydrazino-4,6-dimethylpyrimidine (1 g, 52% yield) as a white solid. The product was confirmed by mass spectrometry (ESI+) with a m/z of 139 (MH+). | [References]
[1] Patent: WO2012/154880, 2012, A1. Location in patent: Page/Page column 60
[2] Journal of the Chemical Society, 1952, p. 4691,4694
[3] Farmaco, Edizione Scientifica, 1956, vol. 11, p. 389,393
[4] Farmaco, Edizione Scientifica, 1983, vol. 38, # 4, p. 255 - 264
[5] Chemistry of Heterocyclic Compounds (New York, NY, United States), 1989, vol. 25, # 12, p. 1369 - 1373 |
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