ChemicalBook--->CAS DataBase List--->2395839-96-8

2395839-96-8

2395839-96-8 Structure

2395839-96-8 Structure
IdentificationBack Directory
[Name]

m-PEG24-NHS ester
[CAS]

2395839-96-8
[Synonyms]

m-PEG23-NHS ester
[Molecular Formula]

C54H103NO28
[MDL Number]

MFCD11041155
[MOL File]

2395839-96-8.mol
[Molecular Weight]

1214.39
Chemical PropertiesBack Directory
[Boiling point ]

967.4±75.0 °C(Predicted)
[density ]

1.18±0.1 g/cm3(Predicted)
[storage temp. ]

Storage temp. -20°C
[form ]

Solid
[color ]

White to off-white
[InChIKey]

VACCUKVGLYJBJU-UHFFFAOYSA-N
[SMILES]

C(ON1C(=O)CCC1=O)(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P280-P301+P312-P302+P352-P305+P351+P338
Hazard InformationBack Directory
[Description]

m-PEG24-NHS ester is a PEG linker containing an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The hydrophilic PEG spacer increases solubility in aqueous media.
[Uses]

m-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50]

PEGs; Alkyl/ether
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Spectrum DetailBack Directory
[Spectrum Detail]

m-PEG24-NHS ester(2395839-96-8)1HNMR
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