| Identification | Back Directory | [Name]
L-Isoleucine, L-isoleucyl-L-arginyl-L-isoleucyl-L-isoleucyl-L-leucyl-L-arginyl-L-alanyl-L-glutaminylglycyl-L-alanyl-L-leucyl-L-lysyl- | [CAS]
2396407-35-3 | [Synonyms]
L-Isoleucine, L-isoleucyl-L-arginyl-L-isoleucyl-L-isoleucyl-L-leucyl-L-arginyl-L-alanyl-L-glutaminylglycyl-L-alanyl-L-leucyl-L-lysyl- | [Molecular Formula]
C67H125N21O15 | [MOL File]
2396407-35-3.mol | [Molecular Weight]
1464.84 |
| Chemical Properties | Back Directory | [density ]
1.33±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [pka]
3.38±0.10(predicted) | [Sequence]
Ile-Arg-Ile-Ile-Leu-Arg-Ala-Gln-Gly-Ala-Leu-Lys-Ile |
| Hazard Information | Back Directory | [Uses]
BING is an antimicrobial peptide that can be isolated from Japanese medaka fish. BING shows a broad-spectrum toxicity against pathogenic bacteria including drug-resistant strains. BING induces a deregulation of periplasmic peptidyl-prolyl isomerases in gram-negative bacteria, and reduces the RNA level of cpxR, which plays a crucial role in the development of antimicrobial resistance[1]. | [References]
[1] Dong M, et al. BING, a novel antimicrobial peptide isolated from Japanese medaka plasma, targets bacterial envelope stress response by suppressing cpxR expression. Sci Rep. 2021 Jun 9;11(1):12219. DOI:10.1038/s41598-021-91765-4 |
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| Company Name: |
YantaiBio
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| Telephone: |
13758194781; 13758194781 |
| Website: |
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| Company Name: |
Fuan Bio
|
| Telephone: |
15002819872 |
| Website: |
fuanbio.com |
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