| Identification | Back Directory | [Name]
Thiazolo[3,2-a]benzimidazol-3(2H)-one,2-[(2-chlorophenyl)methylene]- | [CAS]
23983-05-3 | [Synonyms]
WAY-300033
2-(2-Chlorobenzylidene)benzo[4,5]imidazo[2,1-b]thiazol-3(2H)-one
Thiazolo[3,2-a]benzimidazol-3(2H)-one,2-[(2-chlorophenyl)methylene]- | [Molecular Formula]
C16H9ClN2OS | [MOL File]
23983-05-3.mol | [Molecular Weight]
312.77 |
| Chemical Properties | Back Directory | [Melting point ]
235 °C | [Boiling point ]
524.8±60.0 °C(Predicted) | [density ]
1.47±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
0.56±0.20(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
WT-TTR inhibitor 1 (Compound 21) is a wild-type Transthyretin (WT-TTR) inhibitor with 29.05% inhibition at 100 μM[1]. | [References]
[1] Avadhesha Surolia. Mechanism-based inhibitors of transthyretin amyloidosis: studies with biphenyl ethers and structural templates. Patent US20100190832A1. |
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