| Identification | Back Directory | [Name]
2-(1-naphthylmethylene)[1,3]thiazolo[3,2-a]benzimidazol-3(2H)-one | [CAS]
877468-30-9 | [Synonyms]
WAY-620520
2-(1-naphthylmethylene)[1,3]thiazolo[3,2-a]benzimidazol-3(2H)-one
(Z)-2-(Naphthalen-1-ylmethylene)benzo[4,5]imidazo[2,1-b]thiazol-3(2H)-one
Thiazolo[3,2-a]benzimidazol-3(2H)-one, 2-(1-naphthalenylmethylene)-, (2Z)- | [Molecular Formula]
C20H12N2OS | [MOL File]
877468-30-9.mol | [Molecular Weight]
328.39 |
| Chemical Properties | Back Directory | [Melting point ]
213-215 °C(Solv: acetic acid (64-19-7)) | [Boiling point ]
579.8±53.0 °C(Predicted) | [density ]
1.37±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
1.19±0.20(Predicted) | [color ]
Light yellow to brown |
| Hazard Information | Back Directory | [Uses]
Anti-inflammatory agent 42 (Compound 10j) is an anti-inflammatory agent. Anti-inflammatory agent 42 shows excellent inhibition on the expression of TNF-α and IL-6 in LPS (HY-D1056)-stimulated macrophages[1]. | [References]
[1] Hu J, et al. Synthesis and biological evaluation of novel thiazolidinone derivatives as potential anti-inflammatory agents. Eur J Med Chem. 2013 Jun;64:292-301. DOI:10.1016/j.ejmech.2013.04.010 |
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