| Identification | Back Directory | [Name]
L-Glutamic acid, N-[4-[[ (2-amino-1, 4-dihydro-4-oxo-6-pteridinyl)meth yl]methylamino]benzoyl]- | [CAS]
2410-93-7 | [Synonyms]
NSC 107144
N(10)-methylfolate
N10-Methylfolic acid
Methotrexate-EP-Imp-C
Methotrexate EP IMpurity C
Methotrexate Impurity 3(EP-C)
10-Methylpteroylglutamic acid
N10-MethylpteroylglutaMic Acid
Methotrexate Related CoMpound C
Methotrexate imp C (Mono oxo imp)
Methotrexate Impurity 3（Methotrexate EP Impurity C）
Methotrexate EP Impurity C（Amethopterin EP Impurity C）
2-[(2-Hydroxy-4,5-dimethoxybenzoyl)amino]-4-thiazolecarboxylic Acid
N-[4-[Methyl(2-amino-4-hydroxypteridine-6-ylmethyl)amino]benzoyl]glutamic acid
N-[p-[[(2-AMino-4-hydroxy-6-pteridinyl)Methyl]MethylaMino]
benzoyl]glutaMic Acid
N-[p-[[(2-Amino-4-hydroxypteridin-6-yl)methyl]methylamino]benzoyl]-L-glutamic acid
N-[4-[[(2-Amino-4-hydroxy-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid
2-[[4-[(2-Amino-4-Oxo-1H-Pteridin-6-Yl)Methyl-Methylamino]Benzoyl]Amino]Pentanedioic Acid
N-[4-[[(2-AMino-3,4-dihydro-4-oxo-6-pteridinyl)Methyl]MethylaMino]benzoyl]-L-glutaMic Acid
N-[p-[[(2-AMino-3,4-dihydro-4-oxo-6-pteridinyl)Methyl]MethylaMino]benzoyl]- L-glutaMic Acid
N-[4-[[(2-AMino-1,4-dihydro-4-oxo-6-pteridinyl)
Methyl]MethylaMino]benzoyl]-L-glutaMic Acid
L-Glutamic acid,N-[4-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]methylamino]benzoyl]-
L-Glutamic acid, N-[4-[[ (2-amino-1, 4-dihydro-4-oxo-6-pteridinyl)meth yl]methylamino]benzoyl]-
(2S)-2-[[4-[[(2-amino-4-hydroxy pteridin-6-yl) methyl] methyl amino] benzoyl] amino] pentanedioic acid
Methotrexate Related Compound C (50 mg) ((S)-2-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl](methyl)amino}benzamido) pentanedioic acid)
Methotrexate EP Impurity C/Methotrextae 4-Oxo Analog/N-Methylfolic acid/(2S)-2-[[4-[[(2-amino-4-hydroxy pteridin-6-yl)methyl]methyl amino] benzoyl]amino]pentanedioic acid | [Molecular Formula]
C20H21N7O6 | [MOL File]
2410-93-7.mol | [Molecular Weight]
455.42 |
| Chemical Properties | Back Directory | [Melting point ]
144 - 150°C | [density ]
1.61±0.1 g/cm3(Predicted) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
DMF (Slightly, Heated), DMSO (Slightly) | [form ]
neat | [pka]
3.49±0.10(Predicted) | [color ]
Pale Brown to Brown | [Major Application]
pharmaceutical (small molecule) | [InChIKey]
HLIXOCXUWGDBNP-UHFFFAOYSA-N | [SMILES]
N(Cc2nc3c(nc(nc3O)N)nc2)(C)c1ccc(cc1)C(=O)NC(CCC(=O)O)C(=O)O |
| Hazard Information | Back Directory | [Uses]
2-[(2-Hydroxy-4,5-dimethoxybenzoyl)amino]-4-thiazolecarboxylic Acid is an impurity of Acotiamide (A190260), an acetylcholinesterase inhibitor which has been shown to stimulate gastric motility and improve gastric motility dysfunction in rats. Acotiamide Hydrochloride has also been shown to improve meal-related symptoms of functional dyspepsia. | [Definition]
ChEBI: Methopterine is a member of folic acids. |
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