| Identification | Back Directory | [Name]
Sulfamic acid, 4-[(tricyclo[3.3.1.13,7]dec-1-ylcarbonyl)amino]phenyl ester | [CAS]
2413880-39-2 | [Synonyms]
Steroid sulfatase-IN-2
Sulfamic acid, 4-[(tricyclo[3.3.1.13,7]dec-1-ylcarbonyl)amino]phenyl ester | [Molecular Formula]
C17H22N2O4S | [MOL File]
2413880-39-2.mol | [Molecular Weight]
350.43 |
| Hazard Information | Back Directory | [Uses]
Steroid sulfatase -IN-2 is an active steroid sulfatase (STS) inhibitor with an IC50 value of 109.5 nM. Steroid sulfatase-IN-2 can be used for the research of hormone-dependent cancers, such as estrogen-dependent breast and endometrial cancer[1]. | [References]
[1] Mohammed I El-Gamal, et al. A new series of aryl sulfamate derivatives: Design, synthesis, and biological evaluation. Bioorg Med Chem. 2020 Apr 15;28(8):115406. DOI:10.1016/j.bmc.2020.115406 |
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