| Identification | Back Directory | [Name]
7-CHLORO-1-HYDROXYISOQUINOLINE | [CAS]
24188-74-7 | [Synonyms]
7-Chloroisoquinolin-1-ol
7-CHLORO-1(2H)-ISOQUINOLONE
7-chloro-2H-isoquinolin-1-one
7-Chloro-1(2H)-isoquinolinone
7-CHLORO-1-HYDROXYISOQUINOLINE
1(2H)-Isoquinolinone, 7-chloro- | [Molecular Formula]
C9H6ClNO | [MDL Number]
MFCD08436984 | [MOL File]
24188-74-7.mol | [Molecular Weight]
179.6 |
| Chemical Properties | Back Directory | [Melting point ]
245-247 °C(Solv: methanol (67-56-1)) | [Boiling point ]
414.9±45.0 °C(Predicted) | [density ]
1.339±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [pka]
11.99±0.20(Predicted) |
| Hazard Information | Back Directory | [Uses]
7-Chloroisoquinolin-1(2H)-one acts as a reagent for the preparation, SAR of methoxyisoquinoline derivative and discovery of asunaprevir (BMS-650032), an orally efficacious NS3 protease inhibitor for the treatment of hepatitis C virus infection. Synthesis and pharmacological evaluation of a series of 1,2-dihydro-1-[(5-methyl-1-imidazol-4-yl)methyl]-2-oxopyridine 5-HT3 antagonists. |
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