| Identification | Back Directory | [Name]
ALLOCRYPTOPINE | [CAS]
24240-04-8 | [Synonyms]
Nsc148824
Fagarine i
ALLOCRYPTOPINE
β-Allocryptopine
ALPHA-ALLOCRYPTOPINE
.beta.-Allocryptopine
ALLOCRYPTOPINE, ALPHA-
.gamma.-Homochelidonine
Benzo[E][1,3]dioxolo[4,5-K][3]benzazecin-14(6H)-one, 5,7,8,15-tetrahydro-3,4-dimethoxy-6-methyl-
3,4-DIMETHOXY-6-METHYL-5,7,8,15-TETRAHYDRO-6H-BENZO[C][1,3]DIOXOLO[4',5':4,5]BENZO[1,2-G]AZECIN-14-ONE | [Molecular Formula]
C21H23NO5 | [MDL Number]
MFCD00022318 | [MOL File]
24240-04-8.mol | [Molecular Weight]
369.41 |
| Chemical Properties | Back Directory | [Melting point ]
169-170 °C | [Boiling point ]
552.7±50.0 °C(Predicted) | [density ]
1.216±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
7.86±0.20(Predicted) | [biological source]
plant | [Water Solubility ]
water: slightly soluble |
| Hazard Information | Back Directory | [Uses]
It is a natural product derived from plant source th at finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research. | [Definition]
ChEBI: Allocryptopine is a dibenzazecine alkaloid, an organic heterotetracyclic compound, a tertiary amino compound, a cyclic ketone, a cyclic acetal and an aromatic ether. | [Biological Activity]
Allocryptopine has been reported to possess strong antibacterialanti-inflammatotyantiparasiticantineoplastic and anti-addictive activities. Allocryptopine inhibits human acetylcholinesterase and butyrylcholinesterase. It blocks hERG current in HEK293 cells. Allocryptopine strongly enhanced the I(peak) of the T353I channel by enhancing the plasma membrane (PM) expression of Nav1.5 and rescued defective trafficking after co-incubation with HEK293 cells th at carry mutation channel 24 h. | [target]
cAMP | P450 (e.g. CYP17) |
|
| Company Name: |
BioBioPha Co., Ltd.
|
| Tel: |
0871-65217109 13211707573; |
| Website: |
http://www.biobiopha.com |
|