| Identification | Back Directory | [Name]
Momethyl kolavate | [CAS]
24513-41-5 | [Synonyms]
Momethyl kolavate
MonoMethyl kolavate
(-)- 5,9-Dimethyl-17,19-dinor-8betaH-labda-3,13-diene-15,18-dioic acid 15-methyl ester
1-Naphthalenecarboxylic acid, 3,4,4a,5,6,7,8,8a-octahydro-5-[(3E)-5-methoxy-3-methyl-5-oxo-3-penten-1-yl]-5,6,8a-trimethyl-, (4aR,5S,6R,8aR)- | [Molecular Formula]
C21H32O4 | [MDL Number]
MFCD20260588 | [MOL File]
24513-41-5.mol | [Molecular Weight]
348.48 |
| Hazard Information | Back Directory | [Uses]
Monomethyl kolavate is a Trypanosoma brucei GAPDH enzyme (TbGAPDH) inhibitor with theIC50 value of 2 μM[1]. | [References]
[1] Fabian C Herrmann, et al. In Silico Identification and in Vitro Activity of Novel Natural Inhibitors of Trypanosoma brucei Glyceraldehyde-3-phosphate-dehydrogenase. Molecules. 2015 Sep 3;20(9):16154-69. DOI:10.3390/molecules200916154 |
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