ChemicalBook--->CAS DataBase List--->24589-77-3

24589-77-3

24589-77-3 Structure

24589-77-3 Structure
IdentificationMore
[Name]

4-Hydrazinobenzoic acid hydrochloride
[CAS]

24589-77-3
[Synonyms]

4-CARBOXYPHENYLHYDRAZINE HYDROCHLORIDE
4-HYDRAZINOBENZOIC ACID HCL
4-HYDRAZINOBENZOIC ACID HYDROCHLORIDE
BIO-FARMA BF001082
LABOTEST-BB LT01596126
P-CARBOXYPHENYL HYDRAZINE HCL
P HYDRAZINOBENZOIC ACID HYDROCHLORIDE
4-hydrazino-benzoicacimonohydrochloride
4-hydrazinobenzoic acid monohydrochloride
4-HYDRAZINOBENZOIC ACID HYDROCHLORIDE, 9 8%
[EINECS(EC#)]

246-330-0
[Molecular Formula]

C7H9ClN2O2
[MDL Number]

MFCD00039073
[Molecular Weight]

188.61
[MOL File]

24589-77-3.mol
Chemical PropertiesBack Directory
[Appearance]

white to light yellow crystal powder     
[Melting point ]

253 °C (dec.)(lit.)
[storage temp. ]

2-8°C
[solubility ]

DMSO (Slightly), Methanol (Sparingly)
[form ]

Solid
[color ]

White to Off-White
[Water Solubility ]

Soluble in water.
[InChI]

InChI=1S/C7H8N2O2.ClH/c8-9-6-3-1-5(2-4-6)7(10)11;/h1-4,9H,8H2,(H,10,11);1H
[InChIKey]

XHLQMKQBCHYRLC-UHFFFAOYSA-N
[SMILES]

C1(C(=O)O)=CC=C(NN)C=C1.Cl
[CAS DataBase Reference]

24589-77-3(CAS DataBase Reference)
[EPA Substance Registry System]

24589-77-3(EPA Substance)
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
[WGK Germany ]

3
[RTECS ]

DH1700000
[TSCA ]

Yes
[HS Code ]

2928009090
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Hazard InformationBack Directory
[Chemical Properties]

white to light yellow crystal powder     
[Uses]

4-Hydrazinobenzoic acid hydrochloride is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff fields. It may be used for the preparation of 4-(3-(2-(tert-butoxycarbonylamino)ethyl)-5-hydroxy-1H-pyrazol-1-yl)benzoic acid.
[General Description]

4-Hydrazinobenzoic acid (p-Hydrazinobenzoic acid, HBA) has been reported as an ingredient of the cultivated mushroom Agaricus bisporus. It is carcinogenic to rodents. Mechanism of DNA damage by 4-hydrazinobenzoic acid has been studied by using 32P-labeled DNA fragments obtained from the human p53 and p16 tumor suppressor genes. It may be used for the preparation of 4-(3-(2-(tert-butoxycarbonylamino)ethyl)-5-hydroxy-1H-pyrazol-1-yl)benzoic acid.
[Synthesis]

To 600 ml beaker add water 150 ml, stirring, add p-aminobenzoic acid 27.4 g, 10N hydrochloric acid 57.5 ml, after cooling the solution to 0 ℃, slowly add sodium nitrite solution (from 15 grams of sodium nitrite and 30 ml of water to formulate), add the

Spectrum DetailBack Directory
[Spectrum Detail]

4-Hydrazinobenzoic acid hydrochloride(24589-77-3)1HNMR
Well-known Reagent Company Product InformationBack Directory
[Alfa Aesar]

4-Hydrazinobenzoic acid hydrochloride, 98%(24589-77-3)
[Sigma Aldrich]

24589-77-3(sigmaaldrich)
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