| Hazard Information | Back Directory | [Description]
BAY38-7690 is a hepatitis B virus inhibitor. BAY38-7690 may have potential for future therapeutic regimens to combat chronic HBV infection. | [Uses]
BAY38-7690 is a non-nucleoside inhibitor that inhibits HBV replication. BAY38-7690 inhibits viral DNA replication by preventing the formation of viral core particles (nucleocapsids). The IC50 value of BAY38-7690 against HBV in stably transfected HepG2.2.15 cells is 0.15 μM[1]. | [References]
[1] Deres K, et al. Inhibition of hepatitis B virus replication by drug-induced depletion of nucleocapsids[J]. Science, 2003, 299(5608): 893-896. DOI:10.1126/science.1077215 |
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