| Identification | Back Directory | [Name]
2,5-Cyclohexadiene-1,4-dione,2,5-bis(4-ethylphenyl)-3,6-dihydroxy- | [CAS]
24909-18-0 | [Synonyms]
NSC114126
2,5-Cyclohexadiene-1,4-dione,2,5-bis(4-ethylphenyl)-3,6-dihydroxy- | [Molecular Formula]
C22H20O4 | [MOL File]
24909-18-0.mol | [Molecular Weight]
348.392 |
| Hazard Information | Back Directory | [Uses]
NSC114126 is a potent and orally active inhibitor of EGFR tyrosine kinase (EGFR-TK). NSC114126 has strong antiproliferative activities. NSC114126 has the potential for the research of cancer diseases[1]. | [References]
[1] Jiwacharoenchai N, et al. Discovery of potent antiproliferative agents from selected oxygen heterocycles as EGFR tyrosine kinase inhibitors from the U.S. National Cancer Institute database by in silico screening and bioactivity evaluation. Bioorg Med Chem DOI:10.1016/j.bmcl.2021.128524 |
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