| Identification | Back Directory | [Name]
INDEX NAME NOT YET ASSIGNED | [CAS]
2504068-28-2 | [Synonyms]
MC-Val-Cit-PAB-DX8951 | [Molecular Formula]
C53H60FN9O12 | [Molecular Weight]
1034.09 |
| Chemical Properties | Back Directory | [Boiling point ]
1350.1±65.0 °C(Predicted) | [density ]
1.45±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
10.74±0.40(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Biological Activity]
MC-Val-Cit-PAB-DX8951 is a drug-linker conjugate for ADC. MC-Val-Cit-PAB-DX8951 is composed of a DNA topoisomerase I DX-8951 and a cathepsin cleavable ADC linker.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. | [References]
[1]. Anish Thomas, et al. Antibody-drug conjugates for cancer therapy. Lancet Oncol. 2016 Jun;17(6):e254-e262. |
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| Company Name: |
yaoyangpharm
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| Tel: |
17739007752 17324281842 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList1360066/0.htm |
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