| Chemical Properties | Back Directory | [Boiling point ]
1350.1±65.0 °C(Predicted) | [density ]
1.45±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
10.74±0.40(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
MC-Val-Cit-PAB-Exatecan (MC-Val-Cit-PAB-DX8951) is a agent-linker conjugate for ADC. MC-Val-Cit-PAB-Exatecan is composed of a DNA topoisomerase I DX-8951 (HY-13631) and a cathepsin cleavable ADC linker. | [Biological Activity]
MC-Val-Cit-PAB-DX8951 is a drug-linker conjugate for ADC. MC-Val-Cit-PAB-DX8951 is composed of a DNA topoisomerase I DX-8951 and a cathepsin cleavable ADC linker.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. | [IC 50]
Camptothecins | [References]
[1]. Anish Thomas, et al. Antibody-drug conjugates for cancer therapy. Lancet Oncol. 2016 Jun;17(6):e254-e262. |
| Spectrum Detail | Back Directory | [Spectrum Detail]
L-Ornithinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[[[(1S,9S)-9-ethyl-5-fluoro-2,3,9,10,13,15-hexahydro-9-hydroxy-4-methyl-10,13-dioxo-1H,12H-benzo[de]pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-1-yl]amino]carbonyl]oxy]methyl]phenyl]-(2504068-28-2)1HNMR
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| Company Name: |
YJ Pharma
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| Tel: |
13962794339 13962794339; |
| Website: |
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| Company Name: |
Biomatrik Inc.
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| Tel: |
0573-82623377 18967387295 |
| Website: |
www.biomatrik.cn |
| Company Name: |
yaoyangpharm
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| Tel: |
17739007752 17324281842 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList1360066/0_EN.htm |
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