| Identification | Back Directory | [Name]
2-[(2S)-1-[(1,1-diMethylethoxy)carbonyl]2-pyrrolidinyl]-4-thiazolecarboxylic acid | [CAS]
251349-54-9 | [Synonyms]
Antibiotic-5d
(S)-2-(1-(tert-butoxycarbonyl)pyrrolidin-2-yl)thiazole-4-carboxylic acid
2-[(2S)-1-[(tert-butoxy)carbonyl]pyrrolidin-2-yl]-1,3-thiazole-4-carboxylic acid
2-[(2S)-1-[(1,1-diMethylethoxy)carbonyl]2-pyrrolidinyl]-4-thiazolecarboxylic acid
4-Thiazolecarboxylic acid, 2-[(2S)-1-[(1,1-dimethylethoxy)carbonyl]-2-pyrrolidinyl]- | [Molecular Formula]
C13H18N2O4S | [MDL Number]
MFCD22371193 | [MOL File]
251349-54-9.mol | [Molecular Weight]
298.36 |
| Chemical Properties | Back Directory | [Boiling point ]
459.8±35.0 °C(Predicted) | [density ]
1.317±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 50 mg/mL (167.58 mM) | [form ]
Solid | [pka]
3.73±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Antibiotic-5d is a synthesis and antimicrobial compound. | [Biological Activity]
Antibiotic-5d is a synthetic antimicrobial compound. | [in vitro]
Antibiotic-5d shows moderate antibacterial activity in vitro against various Gram-positive ( Staphylococcus aureus , Bacillus cereus , etc.) and Gram-negative ( < i> Escherichia coli , Proteus vulgaris , etc.) bacteria, fungi ( Candida albicans ), and yeast ( Saccharomyces cerevisae , etc.). | [target]
| [storage]
Store at -20°C | [References]
[1] Stanchev M, et al. Synthesis and antimicrobial activity in vitro of new amino acids and peptides containing thiazole and oxazole moieties. Arch Pharm (Weinheim). 1999 Sep;332(9):297-304. DOI:10.1002/(sici)1521-4184(19999)332:93.0.co;2-# |
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