| Identification | Back Directory | [Name]
acevaltrate | [CAS]
25161-41-5 | [Synonyms]
acevaltrate
Acevaltratum
Acetovaltrate
Acetoxyvaltrate
(Acetyloxy)valepotriate
[(1S,6S,7R,7aS)-4-(acetyloxymethyl)-1-(3-methylbutanoyloxy)spiro[6,7a-dihydro-1H-cyclopenta[c]pyran-7,2'-oxirane]-6-yl] 3-acetyloxy-3-methylbutanoate
3-Acetyloxy-3-methylbutyric acid [(1S,7R)-4-(acetyloxy)methyl-6,7aα-dihydro-1α-(3-methyl-1-oxobutoxy)spiro[cyclopenta[c]pyran-7(1H),2'-oxiran]-6α-yl] ester
3-(Acetyloxy)-3-methylbutanoic acid (1S,2'R,6S,7aS)-4-[(acetyloxy)methyl]-6,7a-dihydro-1-(3-methyl-1-oxobutoxy)spiro[cyclopenta[c]pyran-7(1H),2'-oxiran]-6-yl ester
Butanoic acid,3-(acetyloxy)-3-methyl-,(1S,2'R,6S,7aS)-4-[(acetyloxy)methyl]-6,7a-dihydro-1-(3-methyl-1-oxobutoxy)spiro[cyclopenta[c]pyran-7(1H),2'-oxiran]-6-ylester | [EINECS(EC#)]
246-685-1 | [Molecular Formula]
C24H32O10 | [MDL Number]
MFCD01741123 | [MOL File]
25161-41-5.mol | [Molecular Weight]
480.5 |
| Chemical Properties | Back Directory | [Melting point ]
80-81 °C | [Boiling point ]
538.7±50.0 °C(Predicted) | [density ]
1.26 | [storage temp. ]
2-8°C | [solubility ]
DMSO : ≥ 125 mg/mL (260.15 mM) | [form ]
Solid | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Acevaltrate inhibits the Na+/K+-ATPase activity in the rat kidney and brain hemispheres with IC50s of 22.8 μM and 42.3 μM, respectively[1]. | [Definition]
ChEBI: Acevaltrate is a fatty acid ester. | [References]
[1] Bettero GM, et al. In vitro effect of valepotriates isolated from Valeriana glechomifolia on rat P-type ATPases. Planta Med. 2011 Oct;77(15):1702-6. DOI:10.1055/s-0030-1271084 |
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