| Identification | Back Directory | [Name]
(R)-5-(2-((2-(2-Ethoxyphenoxy)ethyl-1,1,2,2-d4)amino)propyl)-2-methoxybenzenesulfonamide hydrochloride | [CAS]
2518100-55-3 | [Synonyms]
(R)-5-(2-((2-(2-Ethoxyphenoxy)ethyl-1,1,2,2-d4)amino)propyl)-2-methoxybenzenesulfonamide hydrochloride
5-[(2R)-2-[[2-(2-ethoxyphenoxy)ethyl-1,1,2,2-d4]amino]propyl]-2-methoxy-benzenesulfonamide, monohydrochloride | [Molecular Formula]
C20H29ClN2O5S | [MOL File]
2518100-55-3.mol | [Molecular Weight]
444.97 |
| Hazard Information | Back Directory | [Uses]
Tamsulosin-d4 (hydrochloride) is deuterium labeled Tamsulosin (hydrochloride). Tamsulosin hydrochloride ((R)-(-)-YM12617) is an inhibitor of α1-adrenergic receptor. Tamsulosin hydrochloride is used for the research of prostatic hyperplasia. Tamsulosin hydrochloride attenuates abdominal aortic aneurysm growth in animal models[1]. | [References]
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
[2] Christopher Chapple, et al. Tamsulosin: an overview. World J Urol. 2002 Apr;19(6):397-404. DOI:10.1007/s00345-002-0246-7
[3] William G. Montgomery, BA, et al. Tamsulosin Attenuates Abdominal Aortic Aneurysm Growth. Surgery. 2018 Nov; 164(5): 1087-1092. DOI:10.1016/j.surg.2018.06.036 |
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