ChemicalBook--->CAS DataBase List--->2538-68-3

2538-68-3

2538-68-3 Structure

2538-68-3 Structure
IdentificationBack Directory
[Name]

PHENAZINE-1-CARBOXYLIC ACID
[CAS]

2538-68-3
[Synonyms]

emr211
NSC 15851
nrrlb-1482
nrrlb-1576
Tubermycin B
ShenqinMycin
JACS-2538-68-3
Tubermycin (A,B)
1-Carboxyphenazine
Phenazinecarboxylic Acid
1-carboxylicacidphenazine
1-phenazinecarboxylicacid
Phenazine-α-carboxylic Acid
Phenazine-a-carboxylic acid
PHENAZINE-1-CARBOXYLIC ACID
Phenazinecarboxylic acid (6CI)
phenazine-alpha-carboxylicacid
Phenazine-1-carboxylic acid 93%
phenazine-1-carboxylic acid Solution, 100ppm
PHENAZINE-1-CARBOXYLIC ACID ISO 9001:2015 REACH
1-Carboxyphenazine, 1-Carboxydibenzo[b,e]pyrazine
Phenazine-1-carboxylic acid, X-PigMent, ShenqinMycin
Phenazine-1-carboxylic acid Solution in Methanol, 100μg/mL
Phenazinecarboxylicacid (6CI),NSC 15851,Phenazine-a-carboxylic acid,TuberMycin B
[Molecular Formula]

C13H8N2O2
[MDL Number]

MFCD00185184
[MOL File]

2538-68-3.mol
[Molecular Weight]

224.21
Chemical PropertiesBack Directory
[Melting point ]

242-244℃
[Boiling point ]

494.6±10.0 °C(Predicted)
[density ]

1.431±0.06 g/cm3 (20 ºC 760 Torr)
[storage temp. ]

Sealed in dry,Room Temperature
[solubility ]

Chloroform (Slightly), Methanol (Slightly, Heated)
[form ]

Solid
[pka]

2.15±0.30(Predicted)
[color ]

Brown to Orange-Brown
[InChI]

InChI=1S/C13H8N2O2/c16-13(17)8-4-3-7-11-12(8)15-10-6-2-1-5-9(10)14-11/h1-7H,(H,16,17)
[InChIKey]

JGCSKOVQDXEQHI-UHFFFAOYSA-N
[SMILES]

C1(C(O)=O)C2C(=NC3C(N=2)=CC=CC=3)C=CC=1
Safety DataBack Directory
[Symbol(GHS) ]

Skull and Crossbones (GHS06)Health Hazard (GHS08)Environment (GHS09)
GHS06,GHS08,GHS09
[Signal word ]

Danger
[Hazard statements ]

H301+H331-H373-H410
[Precautionary statements ]

P501-P273-P260-P270-P271-P264-P391-P314-P301+P310+P330-P304+P340+P311-P403+P233-P405
[Hazard Codes ]

Xi
[HS Code ]

2917399590
[Toxicity]

LD50 intraperitoneal in mouse: 400mg/kg
Raw materials And Preparation ProductsBack Directory
Hazard InformationBack Directory
[Chemical Properties]

Brown Solid
[Uses]

A microorganism based antimicrobial with high efficiency, low toxicity and good environmental compatibility. A key effective component of the pesticide M18.
[Uses]

Tubermycin B (1-phenazinecarboxylic acid) is a simple phenazine produced by several species of Pseudomonas and Actinomycetes. Tubermycin B is a weakly active antibacterial compound that plays a role in the biocontrol of plant diseases by several Pseudomonas strains. Tubermycin B and related phenazines are important dereplication standards in discovery research to eliminate leads due to high amounts of weakly potent actives.
[Definition]

ChEBI: An aromatic carboxylic acid that is phenazine substituted at C-1 with a carboxy group.
[Synthesis Reference(s)]

Journal of Medicinal Chemistry, 43, p. 1350, 2000 DOI: 10.1021/jm990423f
[in vivo]

Phenazine-1-carboxylic acid (2 and 3 μg/mL, added through E3 medium, single dose) significantly prevented V. anguillaruminfection in zebrafish embryos[4].

Animal Model:Zebrafish embryos infected with Vibrio anguillarum[4]
Dosage:2 μg/mL and 3 μg/mL
Administration:Added through zebrafish embryo E3 medium, single dose
Result:Effectively inhibited V. anguillarum infection in zebrafish embryos and increased embryo hatching rate.
[storage]

Store at -20°C
Spectrum DetailBack Directory
[Spectrum Detail]

Phenazine-1-carboxylic acid(2538-68-3)MS
Phenazine-1-carboxylic acid(2538-68-3)1HNMR
Phenazine-1-carboxylic acid(2538-68-3)IR1
Phenazine-1-carboxylic acid(2538-68-3)IR2
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