| Identification | Back Directory | [Name]
Lonicerin | [CAS]
25694-72-8 | [Synonyms]
LONICERIN
Scolymoside
veronicastroside
LUTEOLIN-7-RUTINOSIDE
Luteolin-7-neohesperidoside
Luteolin 7-beta-neohesperidoside
Lonicerin Luteolin 7-neohesperidoside
Lonicerin（Luteolin-7-O-neohesperidoside）
4H-1-Benzopyran-4-one,7-[[2-O-(6-deoxy-a-L-mannopyranosyl)-b-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-5-hydroxy-
4H-1-Benzopyran-4-one, 7-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-5-hydroxy-
7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxy-oxan-2-yl]oxy-2-(3,4-dihydroxyphenyl)-5-hydroxy-chromen-4-one | [Molecular Formula]
C27H30O15 | [MDL Number]
MFCD31725058 | [MOL File]
25694-72-8.mol | [Molecular Weight]
594.52 |
| Chemical Properties | Back Directory | [Boiling point ]
957.8±65.0 °C(Predicted) | [density ]
1.76±0.1 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,2-8°C | [solubility ]
DMF: 50 mg/ml; DMSO: 50 mg/ml | [form ]
A crystalline solid | [pka]
6.08±0.40(Predicted) | [color ]
Light yellow to yellow | [InChIKey]
SHPPXMGVUDNKLV-KMFFXDMSSA-N | [SMILES]
O1[C@H]([C@@H]([C@@H]([C@H]([C@@H]1C)O)O)O)O[C@H]2[C@@H](O[C@@H]([C@H]([C@@H]2O)O)CO)Oc3cc4[o]c(c[c](c4c(c3)O)=O)c5cc(c(cc5)O)O |
| Hazard Information | Back Directory | [Uses]
Lonicerin is an anti-algE (alginate secretion protein) flavonoid with inhibitory activity for P. aeruginosa. Lonicerin prevents inflammation and apoptosis in LPS-induced acute lung injury[1][2]. | [Definition]
ChEBI: A disaccharide derivative that is luteolin substituted by a 2-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. | [storage]
4°C, protect from light | [References]
[1] Xu Z, et al. Lonicerin, an anti-algE flavonoid against Pseudomonas aeruginosa virulence screened from Shuanghuanglian formula by molecule docking based strategy. J Ethnopharmacol. 2019 Jul 15;239:111909. DOI:10.1016/j.jep.2019.111909
[2] Lee JH, et al. Antiarthritic effect of lonicerin on Candida albicans arthritis in mice. Arch Pharm Res. 2011 May;34(5):853-9.
[3] Xiao Ding, et al. Evaluation of Anti-MRSA and Xanthine Oxidase Inhibition Activities of Phenolic Constituents from Plumula nelumbinis. Journal of Chemistry. 24 December 2015. |
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