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2597186-19-9

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2597186-19-9 Structure

2597186-19-9 Structure
IdentificationBack Directory
[Name]

Imidazo[1,2-a]pyridine-6-carboxamide, N-cyclobutyl-2-[3-[[[[2-(1-piperidinyl)ethyl]amino]sulfonyl]amino]phenyl]-
[CAS]

2597186-19-9
[Synonyms]

N-cyclobutyl-2-(3-((N-(2-(piperidin-1-yl)ethyl)sulfamoyl)amino)phenyl)imidazo[1,2-a]pyridine-6-carboxamide
Imidazo[1,2-a]pyridine-6-carboxamide, N-cyclobutyl-2-[3-[[[[2-(1-piperidinyl)ethyl]amino]sulfonyl]amino]phenyl]-
[Molecular Formula]

C25H32N6O3S
[MDL Number]

MFCD34475601
[MOL File]

2597186-19-9.mol
[Molecular Weight]

496.62
Chemical PropertiesBack Directory
[density ]

1.41±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: 93 mg/mL (187.26 mM);Ethanol: 5 mg/mL (10.07 mM)
[form ]

Solid
[pka]

6.96±0.50(Predicted)
[color ]

White to off-white
[Water Solubility ]

Water: Insoluble
Spectrum DetailBack Directory
[Spectrum Detail]

Imidazo[1,2-a]pyridine-6-carboxamide, N-cyclobutyl-2-[3-[[[[2-(1-piperidinyl)ethyl]amino]sulfonyl]amino]phenyl]-(2597186-19-9)1HNMR
Hazard InformationBack Directory
[Biological Activity]

SR-0813 is a potent and selective ENL/AF9 YEATS domain inhibitor. SR-0813 has IC50 values of 25 and 311 nM for ENL YEATS domain and AF9 YEATS domain, respectively.
[References]

[1] Garnar-Wortzel L, et al. ACS Cent Sci. 2021 May 26;7(5):815-830.
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