| Identification | Back Directory | [Name]
NSC-703786 | [CAS]
260443-89-8 | [Synonyms]
5F203
5F-203
NSC-703786
5-fluoro 203
5F 203
(5F-203
4-(5-Fluorobenzothiazol-2-yl)-2-methylphenylamine
4-(5-Fluoro-2-benzothiazolyl)-2-methyl-benzenamine
4-(5-fluoro-1,3-benzothiazol-2-yl)-2-methylaniline
Benzenamine, 4-(5-fluoro-2-benzothiazolyl)-2-methyl- | [Molecular Formula]
C14H11FN2S | [MDL Number]
MFCD06407710 | [MOL File]
260443-89-8.mol | [Molecular Weight]
258.31 |
| Chemical Properties | Back Directory | [storage temp. ]
2-8°C | [solubility ]
DMSO: soluble20mg/mL, clear | [form ]
powder | [color ]
white to beige | [InChI]
1S/C14H11FN2S/c1-8-6-9(2-4-11(8)16)14-17-12-7-10(15)3-5-13(12)18-14/h2-7H,16H2,1H3 | [InChIKey]
IFWLHIIUGSEKKE-UHFFFAOYSA-N | [SMILES]
Fc1cc2nc([s]c2cc1)c3cc(c(cc3)N)C |
| Hazard Information | Back Directory | [Uses]
5-Fluoro 203 is a cytotoxic agent which actiates AhR signaling, inducing transcription of CYP1A1 which leads to the formation of DNA adducts and cell cycle arrest. | [Biological Activity]
5F-203 is a cytotoxic molecule th at forms DNA adducts th at lead to cell death. 5F-203 induces aryl hydrocarbon receptor signalingand elevates expression of CYP1A1. Treatment of cells with 5F-203 also leads to elevation of reactive oxygen species and activation of p38JNK and ERK. |
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| Company Name: |
Lynnchem
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| Telephone: |
86-(0)29-85992781 17792393971 |
| Website: |
http://www.lynnchem.com/ |
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