| Identification | Back Directory | [Name]
(14R)-2β,3β-Epoxygrayanotoxane-5,6β,10,14,16-pentol 6-acetate | [CAS]
26116-89-2 | [Synonyms]
Rhodojaponin Ⅱ
Rhodojaponin II
(14R)-2β,3β-Epoxygrayanotoxane-5,6β,10,14,16-pentol 6-acetate
(14R)-2β,3β-Epoxygrayanotoxane-5,6β,10,14,16-pentol 6-acetate USP/EP/BP
Grayanotoxane-5,6,10,14,16-pentol,2,3-epoxy-, 6-acetate, (2b,3b,6b,14R)- (9CI)
Grayanotoxane-5,6,10,14,16-pentol, 2,3-epoxy-, 6-acetate, (2β,3β,6β,14R)- (9CI) | [EINECS(EC#)]
300-009-1 | [Molecular Formula]
C22H34O7 | [MDL Number]
MFCD01714941 | [MOL File]
26116-89-2.mol | [Molecular Weight]
410.51 |
| Chemical Properties | Back Directory | [Melting point ]
294.5-296℃ | [Boiling point ]
569.4±50.0 °C(Predicted) | [density ]
1.36±0.1 g/cm3 (20 ºC 760 Torr) | [storage temp. ]
-20°C | [form ]
Solid | [pka]
13.27±0.70(Predicted) | [color ]
White to off-white | [InChI]
1S/C22H34O7/c1-10(23)28-13-8-21-9-19(4,25)11(16(21)24)6-7-12(21)20(5,26)15-14-17(29-14)18(2,3)22(13,15)27/h11-17,24-27H,6-9H2,1-5H3 | [InChIKey]
FJISLLRXVSQIES-UHFFFAOYSA-N | [SMILES]
O=C(C)O[C@H](C[C@]1(C[C@@](C)(O)[C@@H]([C@@H]1O)CC2)[C@]2([H])[C@@]3(C)O)[C@@]4(O)[C@@]3([H])[C@H]5[C@H](O5)C4(C)C |
| Safety Data | Back Directory | [WGK Germany ]
WGK 3 | [Storage Class]
6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials | [Hazard Classifications]
Acute Tox. 2 Dermal
Acute Tox. 2 Oral |
| Hazard Information | Back Directory | [Chemical Properties]
It is a white crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO. It is derived from Rhododendron molle G. Don, a plant of the genus Ericaceae. | [Uses]
Rhodojaponin II is a diterpenoid from the leaves of Rhododendron molle with anti-inflammatory activity[1]. | [References]
[1] Zhou J, et al. Anti-inflammatory Grayanane Diterpenoids from the Leaves of Rhododendron molle. J Nat Prod. 2018 Jan 26;81(1):151-161. DOI:10.1021/acs.jnatprod.7b00799 |
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