| Identification | Back Directory | [Name]
Flubromazepam | [CAS]
2647-50-9 | [Synonyms]
FlubroMazepaM
7-broMo-5-(2-fluorophenyl)-1H-benzo[e][1,4]diazepin-2(3H)-one
7-Bromo-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
7-Bromo-5-(2-fluorophenyl)-1,3-dihydrobenzo[e]-1,4-diazepin-2-one
2H-1,4-Benzodiazepin-2-one, 7-broMo-5-(2-fluorophenyl)-1,3-dihydro- | [EINECS(EC#)]
200-368-4 | [Molecular Formula]
C15H10BrFN2O | [MOL File]
2647-50-9.mol | [Molecular Weight]
333.155 |
| Chemical Properties | Back Directory | [Melting point ]
189-190℃ | [Boiling point ]
465.7±45.0 °C(Predicted) | [density ]
1.58±0.1 g/cm3(Predicted) | [solubility ]
DMF: 25 mg/ml; DMSO: 25 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml; Ethanol: 10 mg/ml; Methanol: 1 mg/ml | [form ]
A crystalline solid | [pka]
11.55±0.70(Predicted) | [CAS DataBase Reference]
2647-50-9 |
| Hazard Information | Back Directory | [Description]
Flubromazepam (Item No. 15157) is an analytical reference standard categorized as a benzodiazepine. Flubromazepam has been detected in seized samples and has anxiolytic and sedative properties. This product is intended for research and forensic applications. | [References]
[1] BJOERN MOOSMANN. Detection and identification of the designer benzodiazepine flubromazepam and preliminary data on its metabolism and pharmacokinetics[J]. Journal of Mass Spectrometry, 2013, 48 11: 1150-1159. DOI: 10.1002/jms.3279
[2] JONES L E, STEWART A, PETERS K L, et al. Infrared and Raman screening of seized novel psychoactive substances: a large scale study of >200 samples?[J]. Analyst, 2016, 3: 902-909. DOI: 10.1039/c5an02326b
[3] RACHELLE ABOUCHEDID. Assessment of the Availability, Cost, and Motivations for Use over Time of the New Psychoactive Substances-Benzodiazepines Diclazepam, Flubromazepam, and Pyrazolam-in the UK.[J]. Journal of Medical Toxicology, 2018, 14 2: 134-143. DOI: 10.1007/s13181-018-0659-3 |
| Questions And Answer | Back Directory | [Uses]
Flubromazepam is a designer benzodiazepine drug structurally related to Phenazepam ; a drug used in the treatment of neurological disorders such as epilepsy, alcohol withdrawal and insomnia. Phenazepam can also be used as a premedication before surgery as it augments the effects of anesthetics and reduces anxiety.
Flubromazepam is a potent, long-acting novel psychoactive benzodiazepine with anxiolytic, anticonvulsant, muscle relaxant and hypnotic properties. Flubromazepam reportedly has a high addiction potential and risk of overdose. This certified Snap-N-Spike® solution is suitable for use as a starting material in calibrators and controls for numerous GC/MS or LC/MS applications in forensic analysis, clinical toxicology and urine drug testing.
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