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2647914-09-6

2647914-09-6 Structure

2647914-09-6 Structure
IdentificationBack Directory
[Name]

INDEX NAME NOT YET ASSIGNED
[CAS]

2647914-09-6
[Synonyms]

(9H-fluoren-9-yl)methyl ((6S,9S)-1-amino-6-((4-(hydroxymethyl)phenyl)carbamoyl)-9-isopropyl-1,8,11,14,17-pentaoxo-2,7,10,13,16-pentaazaoctadecan-18-yl)carbamate
[Molecular Formula]

C39H48N8O9
[MOL File]

2647914-09-6.mol
[Molecular Weight]

772.86
Chemical PropertiesBack Directory
[Boiling point ]

1190.0±65.0 °C(Predicted)
[density ]

1.314±0.06 g/cm3(Predicted)
[form ]

Solid
[pka]

10.61±0.46(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

Fmoc-Gly3-Val-Cit-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
[IC 50]

Protease Cleavable Linker; Cleavable Linker
[References]

[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268
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